SCHEMBL6318272

SCHEMBL6318272

CN(C(=O)OCC1c2ccccc2-c2ccccc21)[C@H](Cc1ccccc1F)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FABP5 Q01469 3/20 0.39
FABP7 O15540 2/20 0.39
KMT2A Q03164 4/20 0.37
PPIA P62937 2/20 0.37
CASP3 P42574 1/20 0.37
PPARG P37231 1/20 0.37
PPARA Q07869 1/20 0.37
MDM4 O15151 1/20 0.36
TP53 P04637 1/20 0.36
MDM2 Q00987 1/20 0.36
MEN1 O00255 1/20 0.36
ATM Q13315 1/20 0.36
NPC1 O15118 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
HTT P42858 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
EPHX2 P34913 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29855060 1.00 FABP5 (0.39) FABP5FABP7KMT2APPIACASP3
SCHEMBL30792882 1.00 FABP5 (0.39) FABP5FABP7KMT2APPIACASP3
SCHEMBL25182263 1.00 FABP5 (0.39) FABP5FABP7KMT2APPIACASP3
SCHEMBL25182264 1.00 FABP5 (0.39) FABP5FABP7KMT2APPIACASP3
SCHEMBL31369420 0.90 KMT2A (0.48) FABP5FABP7KMT2ACASP3MDM4
SCHEMBL31370296 0.89 FABP5 (0.38) FABP5FABP7KMT2APPIACASP3
SCHEMBL29633788 0.89 FABP5 (0.38) FABP5FABP7KMT2APPIACASP3
SCHEMBL31370352 0.88 FABP5 (0.35) FABP5FABP7KMT2ACASP3MDM4
SCHEMBL24633714 0.88 FABP5 (0.40) FABP5FABP7KMT2ACASP3PPARG
SCHEMBL25182166 0.88 FABP5 (0.40) FABP5FABP7KMT2ACASP3PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1499286-A1 STABILIZED BODY CARE PRODUCTS, HOUSEHOLD PRODUCTS, TEXTILES AND FABRICS Ciba SC Holding AG (CH) 2005-01-26 EP claimed
WO-2003103622-A1 STABILIZED BODY CARE PRODUCTS, HOUSEHOLD PRODUCTS, TEXTILES AND FABRICS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-12-18 WO claimed
US-6939880-B2 Compounds with growth hormone releasing properties NOVO NORDISK A/S (DK) 2005-09-06 US disclosed
US-6852731-B2 Antiviral compounds PFIZER (US) 2005-02-08 US disclosed
EP-1499286-A1 STABILIZED BODY CARE PRODUCTS, HOUSEHOLD PRODUCTS, TEXTILES AND FABRICS Ciba SC Holding AG (CH) 2005-01-26 EP disclosed
US-20040242884-A1 ANTIVIRAL COMPOUNDS PHARMACIA & UPJOHN COMPANY 2004-12-02 US disclosed
WO-2003103622-A1 STABILIZED BODY CARE PRODUCTS, HOUSEHOLD PRODUCTS, TEXTILES AND FABRICS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-12-18 WO disclosed
US-6555570-B2 Growth hormone secretagogous with improved bioavailability NOVO NORDISK A/S (DE) 2003-04-29 US disclosed
US-20030055261-A1 Compounds with growth hormone releasing properties HELSINN THERAPEUTICS (U.S.), INC. 2003-03-20 US disclosed
US-20030040483-A1 Compounds with growth hormone releasing properties HELSINN THERAPEUTICS (U.S.), INC. 2003-02-27 US disclosed
US-6127391-A A PEPTIDE MIMETIC COMPOUND FOR STIMULATING THE RELEASE OF GROWTH HORMONE FROM THE PITUITARY NOVO NORDISK A/S (DK) 2000-10-03 US disclosed
US-5977178-A Compounds with growth hormone releasing properties NOVO NORDISK A/S (DK) 1999-11-02 US disclosed
EP-0869974-A1 COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES NOVO NORDISK A/S (DK) 1998-10-14 EP disclosed
WO-1997023508-A1 COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES NOVO NORDISK A/S (DK) 1997-07-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030055261-A1 Compounds with growth hormone releasing properties GHRHR, GHSR, IGFBP1 FABP5 692/4885FABP7 215/4885KMT2A 3089/4885
US-20040242884-A1 ANTIVIRAL COMPOUNDS ZC3HAV1, IRF3, IFNAR1 FABP5 4269/4885FABP7 4599/4885KMT2A 2402/4885
US-20030040483-A1 Compounds with growth hormone releasing properties GHRHR, GHSR, GRPR FABP5 676/4885FABP7 207/4885KMT2A 3144/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.