Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6196460 | 0.88 | ITGB2 (0.51) | ALDH1A1MEN1KMT2ASMN1; SMN2ATM | |
| SCHEMBL6315904 | 0.85 | SMN1; SMN2 (0.45) | ALDH1A1MEN1KMT2ASMN1; SMN2ATM | |
| SCHEMBL6318331 | 0.80 | ITGAL (0.62) | ALDH1A1MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL6199026 | 0.79 | ITGAL (0.52) | ALDH1A1MEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL6196883 | 0.79 | ITGB2 (0.56) | ALDH1A1MEN1KMT2ASMN1; SMN2ATM | |
| SCHEMBL6317025 | 0.79 | ITGAL (0.43) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL6201628 | 0.79 | LGMN (0.47) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL6196585 | 0.78 | ITGB2 (0.53) | ALDH1A1MEN1KMT2ASMN1; SMN2ATM | |
| SCHEMBL6196635 | 0.78 | ITGB2 (0.54) | ALDH1A1SMN1; SMN2KDM4ETSHRCYP2C19 | |
| SCHEMBL6199010 | 0.76 | ITGAL (0.64) | MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6867203-B2 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES (US) | 2005-03-15 | — | — | US | disclosed |
| US-20040116518-A1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES | 2004-06-17 | — | — | US | disclosed |