Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 7/20 | 0.43 |
| ▸ | ITGB2 | P05107 | 6/20 | 0.43 |
| ▸ | ICAM1 | P05362 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7641650 | 0.90 | ITGAL (0.43) | ITGALITGB2ICAM1KMT2AALDH1A1 | |
| SCHEMBL6309661 | 0.88 | MGLL (0.44) | ITGALITGB2ICAM1KMT2AALDH1A1 | |
| SCHEMBL6317717 | 0.87 | ITGAL (0.43) | ITGALITGB2ICAM1KMT2AALDH1A1 | |
| SCHEMBL6310682 | 0.83 | KMT2A (0.49) | ITGALITGB2ICAM1KMT2AALDH1A1 | |
| SCHEMBL6317609 | 0.82 | ITGAL (0.43) | ITGALITGB2ICAM1KMT2AALDH1A1 | |
| SCHEMBL7702269 | 0.82 | ITGB2 (0.48) | ITGALITGB2ICAM1KMT2AALDH1A1 | |
| SCHEMBL6919945 | 0.80 | ITGAL (0.48) | ITGALITGB2ICAM1KMT2AALDH1A1 | |
| SCHEMBL6312040 | 0.79 | ITGAL (0.47) | ITGALITGB2ICAM1KMT2AALDH1A1 | |
| SCHEMBL6318322 | 0.79 | ALDH1A1 (0.50) | KMT2AALDH1A1LMNAMEN1SMN1; SMN2 | |
| SCHEMBL6318620 | 0.79 | ITGAL (0.43) | ITGALITGB2ICAM1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6867203-B2 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES (US) | 2005-03-15 | — | — | US | disclosed |
| US-20040116518-A1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES | 2004-06-17 | — | — | US | disclosed |