Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | F2R | P25116 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6464901 | 0.83 | TSHR (0.52) | TSHRALDH1A1LMNAUTS2RTDP1 | |
| SCHEMBL739158 | 0.83 | TSHR (0.52) | TSHRALDH1A1LMNAUTS2RTDP1 | |
| SCHEMBL5074600 | 0.82 | FOLH1 (0.43) | TSHRALDH1A1LMNAL3MBTL1HTT | |
| SCHEMBL14436829 | 0.82 | ALDH1A1 (0.41) | TSHRALDH1A1LMNATDP1L3MBTL1 | |
| SCHEMBL156281 | 0.82 | ALDH1A1 (0.66) | TSHRALDH1A1LMNAHTTHSD17B10 | |
| SCHEMBL1532511 | 0.82 | TSHR (0.50) | TSHRALDH1A1LMNAUTS2RTDP1 | |
| SCHEMBL28790653 | 0.80 | ALDH1A1 (0.41) | TSHRALDH1A1LMNAHSD17B10KMT2A | |
| SCHEMBL1119555 | 0.80 | TSHR (0.50) | TSHRALDH1A1LMNATDP1L3MBTL1 | |
| SCHEMBL12814338 | 0.80 | TSHR (0.48) | TSHRALDH1A1LMNAUTS2RTDP1 | |
| SCHEMBL8438433 | 0.80 | ALDH1A1 (0.50) | TSHRALDH1A1LMNAUTS2RTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102115757-A | Biosynthetic gene cluster of tiacumicins and application thereof | SOUTH CHINA SEA INST OCEANOLOG | 2011-07-06 | — | — | CN | claimed |
| CN-102115757-B | Platform hooks biological synthesis gene cluster and the application thereof of mycin | SOUTH CHINA SEA INSTITUTE OF OCEANOLOGY, CHINESE ACADEMY OF SCIENCES (CN) | 2015-10-28 | — | — | CN | disclosed |
| CN-102134214-B | Isoindolone compounds and their use as metabotropic glutamate receptor potentiators | ASTRAZENECA AB | 2013-05-22 | — | — | CN | disclosed |
| EP-2419458-A1 | PROCATALYST COMPOSITION WITH SILYL GLUTARATE AND METHOD | Dow Global Technologies LLC (US) | 2012-02-22 | — | — | EP | disclosed |
| CN-102134214-A | Isoindolone compounds and their use as metabotropic glutamate receptor potentiators | ASTRAZENECA SWEDEN AB | 2011-07-27 | — | — | CN | disclosed |
| CN-102115757-A | Biosynthetic gene cluster of tiacumicins and application thereof | SOUTH CHINA SEA INST OCEANOLOG | 2011-07-06 | — | — | CN | disclosed |
| CN-101039907-B | Isoindolone compounds and their use as metabotropic glutamate receptor potentiators | ASTRAZENECA AB | 2011-02-23 | — | — | CN | disclosed |
| WO-2010120973-A1 | PROCATALYST COMPOSITION WITH SILYL GLUTARATE AND METHOD | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-10-21 | — | — | WO | disclosed |
| CN-101039907-A | Isoindolone compounds and their use as metabotropic glutamate receptor potentiators | ASTRAZENECA AB (SE) | 2007-09-19 | — | — | CN | disclosed |
| US-5330949-A | Catalyst supports, silicon dioxide modified with a chlorosilane, an alcohol and a magnesium alkoxide, reduced catalyst residue | IDEMITSU PETROCHEMICAL COMPANY, LTD. (JP) | 1994-07-19 | — | — | US | disclosed |