Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.31 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL339790 | 0.87 | TSHR (0.35) | TSHR | |
| SCHEMBL2025387 | 0.85 | NFKB1 (0.30) | — | |
| SCHEMBL27427022 | 0.83 | — | — | |
| SCHEMBL16497225 | 0.82 | TSHR (0.37) | TSHR | |
| SCHEMBL3481918 | 0.82 | TSHR (0.32) | TSHR | |
| Ammonia Solution, Strong SCHEMBL14579022 | 0.81 | DNM1 (0.31) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL728034 | 0.80 | DNM1 (0.33) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL4770420 | 0.79 | TSHR (0.39) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL10951874 | 0.79 | CYP3A4 (0.31) | ALDH1A1CYP3A4 | |
| SCHEMBL3481529 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6864340-B2 | Hybrid end-capped reactive silicone polymers | HENKEL CORPORATION (US) | 2005-03-08 | — | — | US | claimed |
| US-20030216536-A1 | Hybrid end-capped reactive silicone polymers | Henkel IP & Holding GmbH (DE) | 2003-11-20 | — | — | US | claimed |
| WO-2001083592-A1 | HYBRID END-CAPPED REACTIVE SILICONE POLYMERS | HENKEL LOCTITE CORPORATION (US) | 2001-11-08 | — | — | WO | claimed |