SCHEMBL6318976

SCHEMBL6318976

COc1ccc2cc(C(CNc3ccc(C)nc3C)P3(=O)N[C@@H](C)[C@@H](C)N3)sc2c1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.32
CHRNA7 P36544 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6324062 0.75 CA2 (0.33) CA2CHRNA7
SCHEMBL6254565 0.75 HSD17B10 (0.37) CA2CHRNA7
SCHEMBL6318067 0.73 CA2 (0.34) CA2CHRNA7
SCHEMBL6317265 0.73 CA2 (0.32) CA2CHRNA7
SCHEMBL6256850 0.73 CA2 (0.31) CA2
SCHEMBL6325868 0.73 HSD17B10 (0.32) CA2
SCHEMBL6256841 0.73 CA2 (0.33) CA2
SCHEMBL6319871 0.72 ABL1 (0.35) CHRNA7
SCHEMBL6317568 0.72 CA2 (0.36) CA2
SCHEMBL6325412 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050143349-A1 Phosphorus containing compounds useful for the regulation of LDL and Lp(a) levels QUATRX PHARMACEUTICALS CO. 2005-06-30 US claimed
US-20050143349-A1 Phosphorus containing compounds useful for the regulation of LDL and Lp(a) levels QUATRX PHARMACEUTICALS CO. 2005-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050143349-A1 Phosphorus containing compounds useful for the regulation of LDL and Lp(a) levels APOB, LDLR, LPL CA2 2047/4885CHRNA7 4437/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.