SCHEMBL6319090

SCHEMBL6319090

CCOC(=O)c1cnn(-c2cccc3ccccc23)c1C1CC1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 3/20 0.62
SLC9A2 Q9UBY0 2/20 0.62
TP53 P04637 1/20 0.49
POLB P06746 1/20 0.49
CDC25B P30305 2/20 0.47
ALDH1A1 P00352 4/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
KMT2A Q03164 3/20 0.47
MEN1 O00255 2/20 0.47
LMNA P02545 1/20 0.47
GAA P10253 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
HPGD P15428 2/20 0.46
MAPT P10636 2/20 0.46
NPC1 O15118 2/20 0.46
TSHR P16473 1/20 0.46
OPRM1 P35372 1/20 0.46
OPRD1 P41143 1/20 0.46
OPRK1 P41145 1/20 0.46
CDC25A P30304 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6313733 0.91 SLC9A1 (0.52) SLC9A1SLC9A2TP53POLBALDH1A1
SCHEMBL30142173 0.90 SLC9A1 (0.51) SLC9A1SLC9A2TP53POLBALDH1A1
SCHEMBL6314722 0.90 SLC9A1 (0.51) SLC9A1SLC9A2TP53POLBALDH1A1
SCHEMBL6313854 0.86 ALDH1A1 (0.50) SLC9A1SLC9A2TP53POLBALDH1A1
SCHEMBL6313907 0.86 ALDH1A1 (0.50) SLC9A1SLC9A2TP53POLBALDH1A1
SCHEMBL6311361 0.85 SLC9A1 (0.65) SLC9A1SLC9A2TP53POLBALDH1A1
SCHEMBL6314818 0.84 ALDH1A1 (0.48) SLC9A1SLC9A2TP53POLBALDH1A1
SCHEMBL6314019 0.84 NPSR1 (0.49) SLC9A1SLC9A2TP53POLBALDH1A1
SCHEMBL6313244 0.84 MEN1 (0.56) TP53POLBALDH1A1SMN1; SMN2KMT2A
SCHEMBL6321366 0.84 NPC1 (0.46) SLC9A1SLC9A2TP53POLBCDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3398983-B1 POLYMER OF POLYIMIDE PRECURSOR, POSITIVE TYPE PHOTOSENSITIVE RESIN COMPOSITION, NEGATIVE TYPE PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING PROCESS, METHOD FOR FORMING CURED FILM, INTERLAYER INSULATING FILM, SURFACE PROTECTIVE FILM, AND ELECTRONIC PARTS SHINETSU CHEMICAL CO (JP) 2023-09-27 EP disclosed
US-11150556-B2 Polymer of polyimide precursor, positive type photosensitive resin composition, negative type photosensitive resin composition, patterning process, method for forming cured film, interlayer insulating film, surface protective film, and electronic parts SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-10-19 US disclosed
EP-3398983-A1 POLYMER OF POLYIMIDE PRECURSOR, POSITIVE TYPE PHOTOSENSITIVE RESIN COMPOSITION, NEGATIVE TYPE PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING PROCESS, METHOD FOR FORMING CURED FILM, INTERLAYER INSULATING FILM, SURFACE PROTECTIVE FILM, AND ELECTRONIC PARTS Shin-Etsu Chemical Co., Ltd. (JP) 2018-11-07 EP disclosed
US-20180275513-A1 POLYMER OF POLYIMIDE PRECURSOR, POSITIVE TYPE PHOTOSENSITIVE RESIN COMPOSITION, NEGATIVE TYPE PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING PROCESS, METHOD FOR FORMING CURED FILM, INTERLAYER INSULATING FILM, SURFACE PROTECTIVE FILM, AND ELECTRONIC PARTS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-09-27 US disclosed
US-6974813-B2 N-[(substituted five-membered di-or triaza diunsaturated ring) carbonyl] guanidine derivatives for the treatment of ischemia WARNER-LAMBERT COMPANY (US) 2005-12-13 US disclosed
US-6946233-B2 High resolution; etching chemical resistance SHIN-ETSU CHEMICAL CO., LTD. (JP) 2005-09-20 US disclosed
US-20050142491-A1 Novel epoxy compounds having an alicyclic structure, polymer compounds, resist materials, and patterning methods HASEGAWA KOJI (JP) 2005-06-30 US disclosed
EP-1454902-A1 N- (substituted five-membered di-or triaza diunsaturated ring)carbonyl guanidine derivateives for the treatment of ischemia Pfizer Products Inc. (US) 2004-09-08 EP disclosed
US-20030149043-A1 N-[(substituted five-membered di-or triaza diunsaturated ring)carbonyl] guanidine derivatives for the treatment of ischemia PFIZER INC. 2003-08-07 US disclosed
US-20030054290-A1 Polymer, resist material and patterning method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2003-03-20 US disclosed
US-20030050398-A1 Novel epoxy compounds having an alicyclic structure, polymer compounds, resist materials, and patterning methods SHIN-ETSU CHEMICAL CO., LTD. (JP) 2003-03-13 US disclosed
US-6492401-B1 SODIUM HYDROGEN EXCHANGER TYPE 1 INHIBITORS; REDUCING PERIOPERATIVE MYOCARDIAL TISSUE DAMAGE PFIZER, INC. 2002-12-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030149043-A1 N-[(substituted five-membered di-or triaza diunsaturated ring)carbonyl] guanidine derivatives for the treatment of ischemia NHERF1, SLC28A1, TNNI3 SLC9A1 5/4885SLC9A2 12/4885TP53 4706/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.