Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.34 |
| ▸ | ITK | Q08881 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | WNT3A | P56704 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6319871 | 0.66 | ABL1 (0.35) | ABL1CHRNA7 | |
| SCHEMBL6326060 | 0.65 | ABL1 (0.33) | ABL1ITKMAPTNPC1RAB9A | |
| SCHEMBL6324560 | 0.62 | ABL1 (0.33) | ABL1 | |
| SCHEMBL6318633 | 0.59 | MAPT (0.34) | ABL1CHRNA7MAPTNPC1RAB9A | |
| SCHEMBL6325628 | 0.59 | NPC1 (0.31) | ITKMAPTNPC1RAB9ALMNA | |
| SCHEMBL13632617 | 0.59 | CA2 (0.54) | MAPTALDH1A1TSHRCYP2C19SMN1; SMN2 | |
| SCHEMBL13632618 | 0.58 | CA2 (0.41) | CHRNA7ITKMAPTNPC1RAB9A | |
| SCHEMBL9808648 | 0.56 | CA2 (0.47) | CHRNA7MAPTRAB9ALMNATP53 | |
| SCHEMBL8599290 | 0.56 | CHRNA7 (0.42) | ABL1CHRNA7ITKMAPTNPC1 | |
| SCHEMBL4444144 | 0.55 | CA2 (0.46) | CHRNA7CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6972271-B2 | Supported catalyst systems | HONEYWELL INTERNATIONAL INC. (US) | 2005-12-06 | — | — | US | claimed |
| US-20050143349-A1 | Phosphorus containing compounds useful for the regulation of LDL and Lp(a) levels | QUATRX PHARMACEUTICALS CO. | 2005-06-30 | — | — | US | claimed |
| US-20050107246-A1 | Supported catalyst systems | HONEYWELL INTERNATIONAL, INC. (US) | 2005-05-19 | — | — | US | claimed |
| US-20020123423-A1 | Supported catalyst systems | HONEYWELL INTERNATIONAL INC. | 2002-09-05 | — | — | US | claimed |
| US-5959151-A | Process for the purification of pentafluorophenyl boron compounds | ALBEMARLE CORPORATION (US) | 1999-09-28 | — | — | US | claimed |
| US-6972271-B2 | Supported catalyst systems | HONEYWELL INTERNATIONAL INC. (US) | 2005-12-06 | — | — | US | disclosed |
| US-20050143349-A1 | Phosphorus containing compounds useful for the regulation of LDL and Lp(a) levels | QUATRX PHARMACEUTICALS CO. | 2005-06-30 | — | — | US | disclosed |
| US-20050107246-A1 | Supported catalyst systems | HONEYWELL INTERNATIONAL, INC. (US) | 2005-05-19 | — | — | US | disclosed |
| US-20020123423-A1 | Supported catalyst systems | HONEYWELL INTERNATIONAL INC. | 2002-09-05 | — | — | US | disclosed |
| US-5602217-A | INCREASING THE YIELD BY CATALYTIC ADDITIONAL POLYMERIZING IN PRESENCE OF AT LEAST ONE METALLOCENE AND ONE AGED ALUMOXANE | EXXON CHEMICAL PATENTS INC. (US) | 1997-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143349-A1 | Phosphorus containing compounds useful for the regulation of LDL and Lp(a) levels | APOB, LDLR, LPL | ABL1 3173/4885CHRNA7 4437/4885ITK 4731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.