Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.50 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL347893 | 0.76 | LOXL2 (0.50) | LOXL2HRH1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL254617 | 0.76 | MEN1 (0.52) | LOXL2HRH1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL151822 | 0.76 | LOXL2 (0.68) | LOXL2HRH1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL103124 | 0.75 | ALDH1A1 (0.48) | LOXL2CYP3A4ALDH1A1HSD17B10TDP1 | |
| SCHEMBL2574518 | 0.75 | — | — | |
| SCHEMBL30292864 | 0.74 | CHRNA7 (0.57) | HRH1CYP1A2CYP2D6HRH3TDP1 | |
| SCHEMBL7052160 | 0.74 | CHRNA7 (0.57) | HRH1CYP1A2CYP2D6HRH3TDP1 | |
| Water SCHEMBL31124596 | 0.73 | LOXL2 (0.65) | LOXL2HRH1CYP1A2CYP3A4CYP2D6 | |
| Water SCHEMBL31124597 | 0.73 | LOXL2 (0.65) | LOXL2HRH1CYP1A2CYP3A4CYP2D6 | |
| Ammonia Solution, Strong SCHEMBL9306930 | 0.73 | LOXL2 (0.65) | LOXL2HRH1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105793262-B | Two cycloalkyne derivatives and application thereof | 新加坡科技研究局 | 2019-09-03 | — | — | CN | disclosed |
| US-20050143578-A1 | Compounds and methods | SMITHKLINE BEECHAM CORPORATION | 2005-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143578-A1 | Compounds and methods | METAP2, METAP1, DNPEP | LOXL2 673/4885HRH1 1272/4885HDAC8 2760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.