Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.74 |
| ▸ | FEN1 | P39748 | 1/20 | 0.74 |
| ▸ | CES2 | O00748 | 1/20 | 0.62 |
| ▸ | CES1 | P23141 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | HPGD | P15428 | 6/20 | 0.62 |
| ▸ | POLB | P06746 | 5/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.62 |
| ▸ | RECQL | P46063 | 3/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7070914 | 0.98 | ERCC5 (0.71) | ERCC5FEN1CES2CES1ALDH1A1 | |
| SCHEMBL6510709 | 0.89 | ERCC5 (0.72) | ERCC5FEN1CES2CES1ALDH1A1 | |
| SCHEMBL2026271 | 0.88 | ERCC5 (0.66) | ERCC5FEN1CES2CES1ALDH1A1 | |
| SCHEMBL27839966 | 0.87 | ERCC5 (0.65) | ERCC5FEN1CES2CES1ALDH1A1 | |
| SCHEMBL183688 | 0.87 | ERCC5 (0.65) | ERCC5FEN1CES2CES1ALDH1A1 | |
| SCHEMBL5159962 | 0.87 | ERCC5 (0.65) | ERCC5FEN1CES2CES1ALDH1A1 | |
| SCHEMBL1651850 | 0.86 | CES2 (0.70) | ERCC5FEN1CES2CES1ALDH1A1 | |
| SCHEMBL10356158 | 0.86 | ERCC5 (0.62) | ERCC5FEN1CES2CES1ALDH1A1 | |
| SCHEMBL7124763 | 0.86 | ERCC5 (0.62) | ERCC5FEN1CES2CES1ALDH1A1 | |
| SCHEMBL28064368 | 0.86 | ERCC5 (0.68) | ERCC5FEN1CES2CES1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105348060-A | Preparation method of 1,2-diketone derivative | CHINASUN SPECIALTY PRODUCTS CO LTD | 2016-02-24 | — | — | CN | claimed |
| US-6845823-B2 | Fluorosurfactant-free foam fire-extinguisher | GTL CO., LTD. (JP) | 2005-01-25 | — | — | US | claimed |
| US-6838019-B2 | Phosphorescent material and electroluminescent device using thereof | RITEK CORPORATION (TW) | 2005-01-04 | — | — | US | claimed |
| EP-1454598-A1 | FLUOROSURFACTANT-FREE FOAM FIRE-EXTINGUISHER | GTL CO., LTD. (JP) | 2004-09-08 | — | — | EP | claimed |
| US-20040074650-A1 | Fluorosurfactant-free foam fire-extinguisher | YASUKAWA, NATSUKO (JP) | 2004-04-22 | — | — | US | claimed |
| US-20030102800-A1 | Phosphorescent material | RITEK CORPORATION (TW) | 2003-06-05 | — | — | US | claimed |
| CN-116917317-A | Administration for treatment with anti-CD 20/anti-CD 3 bispecific antibody and anti-CD 79B antibody drug conjugates | 基因泰克公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-110143935-B | Preparation method of 2, 5-disubstituted furan derivative | 华侨大学 | 2022-09-30 | — | — | CN | disclosed |
| CN-115093323-A | Beta-functionalized chiral homoallyl alcohol derivative and preparation method and application thereof | 武汉大学 | 2022-09-23 | — | — | CN | disclosed |
| US-10167303-B2 | Iridium organometallic complex containing a substituted dibenzo[f,h]quinoxaline and an electronic device having an emitting layer containing the iridium complex | UDC IRELAND LIMITED (IE) | 2019-01-01 | — | — | US | disclosed |
| EP-2252624-B1 | ELECTROLUMINESCENT METAL COMPLEXES WITH DIBENZO[F,H]QUINOXALINES | UDC IRELAND LTD (IE) | 2018-07-18 | — | — | EP | disclosed |
| US-10023752-B2 | Conductive material and substrate | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2018-07-17 | — | — | US | disclosed |
| US-10023752-B2 | Conductive material and substrate | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2018-07-17 | — | — | US | disclosed |
| CN-1464027-A | Phosphorescent light-emitting material | LAIDE SCIENCE & TECHNOLOGY CO (CN) | 2003-12-31 | — | — | CN | disclosed |
| US-20030102800-A1 | Phosphorescent material | RITEK CORPORATION (TW) | 2003-06-05 | — | — | US | disclosed |
| US-6521716-B1 | Coating, adhesive and sealant compositions | AKZO NOBEL N.V. (NL) | 2003-02-18 | — | — | US | disclosed |
| EP-0970137-B1 | COATING, ADHESIVE AND SEALANT COMPOSITIONS | INT COATINGS LTD (GB) | 2002-06-12 | — | — | EP | disclosed |
| US-4325962-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIDYRETICS | BYK-GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-04-20 | — | — | US | disclosed |
| US-4176918-A | Fluorescent liquid crystal display | TEMPLE UNIVERSITY (US) | 1979-12-04 | — | — | US | disclosed |
| US-4146721-A | ANALGESICS, ANTIINFLAMMATORY AGENTS AND ANTIPYRETICS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1979-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10167303-B2 | Iridium organometallic complex containing a substituted dibenzo[f,h]quinoxaline and an electronic device having an emitting layer containing the iridium complex | NDUFS5, DDT, NDUFV2 | ERCC5 369/4885FEN1 758/4885CES2 3067/4885 |
| US-20030102800-A1 | Phosphorescent material | PKD1, RPS6KA1, RPS6KA6 | ERCC5 2017/4885FEN1 4327/4885CES2 4818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.