Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | BACE1 | P56817 | 3/20 | 0.41 |
| ▸ | UBE2M | P61081 | 1/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SSTR5 | P35346 | 5/20 | 0.39 |
| ▸ | MLNR | O43193 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 2/20 | 0.38 |
| ▸ | ALPI | P09923 | 2/20 | 0.38 |
| ▸ | ALPG | P10696 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4120483 | 0.84 | ACHE (0.47) | KDM4ELMNAACHEBACE1UBE2M | |
| SCHEMBL5683742 | 0.79 | MEN1 (0.49) | KDM4EBCHETP53ALDH1A1 | |
| SCHEMBL5683863 | 0.76 | MEN1 (0.46) | KDM4EBCHETP53ALDH1A1 | |
| SCHEMBL6322190 | 0.75 | NEK2 (0.49) | KDM4ELMNAHTTSMN1; SMN2ALPL | |
| SCHEMBL13800282 | 0.73 | HCRTR1 (0.34) | KDM4ELMNAACHEBACE1BCHE | |
| Hydrochloric Acid SCHEMBL4116596 | 0.73 | HCRTR1 (0.34) | KDM4ELMNAACHEBACE1BCHE | |
| SCHEMBL6319797 | 0.72 | ALDH1A1 (0.57) | KDM4ESMN1; SMN2TP53ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6319376 | 0.72 | ACHE (0.55) | ACHEBACE1BCHE | |
| SCHEMBL4123414 | 0.72 | ACHE (0.56) | ACHEBACE1UBE2MDCUN1D1BCHE | |
| Hydrochloric Acid SCHEMBL6326446 | 0.70 | ALDH1A1 (0.38) | LMNAACHEBACE1BCHESIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050176764-A1 | Medicine for treating cancer | KOWA CO., LTD (JP) | 2005-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176764-A1 | Medicine for treating cancer | HDAC4, HDAC3, NR4A3 | KDM4E 446/4885LMNA 2246/4885ACHE 4596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.