Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NEK2 | P51955 | 3/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.49 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.49 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.48 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 2/20 | 0.46 |
| ▸ | ALPI | P09923 | 2/20 | 0.46 |
| ▸ | ALPG | P10696 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6319797 | 0.88 | ALDH1A1 (0.57) | L3MBTL1TP53MEN1KMT2AKDM4E | |
| SCHEMBL5683742 | 0.86 | MEN1 (0.49) | TP53MEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL5683863 | 0.82 | MEN1 (0.46) | TP53MEN1KMT2AKDM4EMAPK1 | |
| Maleic Acid SCHEMBL6328233 | 0.81 | KDM4E (0.41) | NEK2PLK1NEK1L3MBTL1ALPL | |
| SCHEMBL4114501 | 0.80 | NEK2 (0.52) | NEK2PLK1NEK1CD274PDCD1 | |
| Fumaric Acid SCHEMBL6328236 | 0.80 | THRB (0.44) | TP53MEN1KMT2ALMNAMAPT | |
| Hydrochloric Acid SCHEMBL6326446 | 0.76 | ALDH1A1 (0.38) | MEN1KMT2ASIGMAR1LMNA | |
| Hydrochloric Acid SCHEMBL4763730 | 0.76 | MEN1 (0.44) | MEN1KMT2A | |
| SCHEMBL28219784 | 0.76 | POLB (0.67) | CD274PDCD1MEN1KMT2ASIGMAR1 | |
| SCHEMBL6320232 | 0.75 | KDM4E (0.44) | ALPLALPIALPGTP53SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050176764-A1 | Medicine for treating cancer | KOWA CO., LTD (JP) | 2005-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176764-A1 | Medicine for treating cancer | HDAC4, HDAC3, NR4A3 | NEK2 205/4885PLK1 3665/4885NEK1 281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.