Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 1.00 |
| ▸ | NPC1 | O15118 | 7/20 | 1.00 |
| ▸ | POLB | P06746 | 5/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | TP53 | P04637 | 1/20 | 1.00 |
| ▸ | HPGD | P15428 | 1/20 | 1.00 |
| ▸ | ALOX12 | P18054 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 1.00 |
| ▸ | RAB9A | P51151 | 8/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.74 |
| ▸ | RECQL | P46063 | 1/20 | 0.73 |
| ▸ | GAA | P10253 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | ALPL | P05186 | 1/20 | 0.68 |
| ▸ | ALPG | P10696 | 1/20 | 0.68 |
| ▸ | CTSZ | Q9UBR2 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6203085 | 0.86 | ALDH1A1 (0.97) | ALDH1A1NPC1POLBMAPTKMT2A | |
| SCHEMBL11887704 | 0.86 | RAB9A (0.75) | ALDH1A1NPC1POLBMAPTKMT2A | |
| SCHEMBL14479868 | 0.80 | POLB (0.76) | ALDH1A1NPC1POLBMAPTKMT2A | |
| SCHEMBL6327761 | 0.80 | ALPL (0.71) | ALDH1A1NPC1POLBMAPTKMT2A | |
| SCHEMBL24943937 | 0.79 | ALDH1A1 (1.00) | ALDH1A1NPC1POLBMAPTKMT2A | |
| SCHEMBL9805593 | 0.77 | ALDH1A1 (0.61) | ALDH1A1NPC1POLBMAPTKMT2A | |
| SCHEMBL14624712 | 0.76 | ALDH1A1 (0.60) | ALDH1A1NPC1POLBMAPTKMT2A | |
| SCHEMBL3764555 | 0.76 | RAB9A (0.60) | ALDH1A1NPC1POLBMAPTKMT2A | |
| Hydrochloric Acid SCHEMBL7423557 | 0.74 | RAB9A (0.58) | ALDH1A1NPC1POLBMAPTKMT2A | |
| SCHEMBL6201829 | 0.73 | CA12 (0.64) | ALDH1A1NPC1POLBMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |