Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | NCOA2 | Q15596 | 3/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 3/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TYMP | P19971 | 3/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.36 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17285587 | 0.95 | ALDH1A1 (0.57) | ALDH1A1MAPTHPGDCYP2C9KMT2A | |
| SCHEMBL17285533 | 0.87 | ALDH1A1 (0.61) | ALDH1A1MAPTHPGDCYP2C9KMT2A | |
| SCHEMBL251649 | 0.85 | TYMP (0.47) | ALDH1A1NPSR1TYMPGPR84HCAR2 | |
| SCHEMBL6316286 | 0.81 | KMT2A (0.39) | ALDH1A1MAPTHPGDKMT2APPARG | |
| SCHEMBL5793071 | 0.79 | MAPT (0.56) | ALDH1A1MAPTHPGDCYP2C9KMT2A | |
| SCHEMBL28213046 | 0.72 | ALDH1A1 (0.52) | ALDH1A1MAPTHPGDKMT2AGPR84 | |
| SCHEMBL5791378 | 0.71 | ALDH1A1 (1.00) | ALDH1A1MAPTHPGDCYP2C9KMT2A | |
| SCHEMBL5795084 | 0.71 | ALDH1A1 (0.63) | ALDH1A1MAPTHPGDKMT2APPARG | |
| SCHEMBL17272789 | 0.71 | MAPT (0.61) | ALDH1A1MAPTHPGDCYP2C9KMT2A | |
| SCHEMBL21925027 | 0.71 | GLA (0.57) | ALDH1A1MAPTHPGDKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6927193-B2 | Aryl ether derivatives and processes for their preparation and herbicidal and desiccant compositions containing them | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2005-08-09 | — | — | US | disclosed |
| US-20040267014-A1 | Aryl ether derivatives and processes for their preparation and herbicidal and desiccant compositions containing them | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2004-12-30 | — | — | US | disclosed |
| EP-1432692-A1 | ARYL ETHER DERIVATIVES AND PROCESSES FOR THEIR PREPARATION AND HERBICIDAL AND DESICCANT COMPOSITIONS CONTAINING THEM | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2004-06-30 | — | — | EP | disclosed |
| US-20030195118-A1 | Aryl ether derivatives and processes for their preparation and herbicidal and desiccant compositions containing them | ISHIHARA SANGYO KAISHA, LTD. | 2003-10-16 | — | — | US | disclosed |
| US-6613718-B2 | 2,3-Dihydro-2-thioxo-pyrimidinone derivatives | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2003-09-02 | — | — | US | disclosed |
| US-20030130122-A1 | Aryl ether derivatives and processes for their preparation and herbicidal and desiccant compositions containing them | ISHIHARA SANGYO KAISHA, LTD. | 2003-07-10 | — | — | US | disclosed |
| WO-2003029225-A1 | ARYL ETHER DERIVATIVES AND PROCESSES FOR THEIR PREPARATION AND HERBICIDAL AND DESICCANT COMPOSITIONS CONTAINING THEM | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2003-04-10 | — | — | WO | disclosed |
| EP-1077954-A1 | SUBSTITUTED 6-ARYL-3-THIOXO-5-(THI)OXO-2,3,4,5-TETRAHYDRO-1,2,4-TRIAZINES | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999059983-A1 | SUBSTITUTED 6-ARYL-3-THIOXO-5-(THI)OXO-2,3,4,5-TETRAHYDRO-1,2,4-TRIAZINES | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130122-A1 | Aryl ether derivatives and processes for their preparation and herbicidal and desiccant compositions containing them | CBR3, CBR1, DDT | ALDH1A1 901/4885MAPT 4604/4885HPGD 2721/4885 |
| US-20030195118-A1 | Aryl ether derivatives and processes for their preparation and herbicidal and desiccant compositions containing them | CBR3, CBR1, DDT | ALDH1A1 906/4885MAPT 4604/4885HPGD 2705/4885 |
| US-20040267014-A1 | Aryl ether derivatives and processes for their preparation and herbicidal and desiccant compositions containing them | CBR3, HDHD5, DDT | ALDH1A1 943/4885MAPT 4506/4885HPGD 3003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.