Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 5/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 3/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.35 |
| ▸ | TXNRD3 | Q86VQ6 | 2/20 | 0.35 |
| ▸ | TXNRD2 | Q9NNW7 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6320578 | 1.00 | MAPT (0.38) | MAPTSMN1; SMN2APPGAAGLO1 | |
| SCHEMBL6317812 | 0.78 | — | — | |
| SCHEMBL6317816 | 0.78 | — | — | |
| SCHEMBL6318095 | 0.71 | KMT2A (0.32) | MAPTSMN1; SMN2GAAALDH1A1KMT2A | |
| SCHEMBL6319409 | 0.69 | GAA (0.33) | MAPTGAACYP2C9HSD17B10KDM4E | |
| SCHEMBL6324972 | 0.68 | SMN1; SMN2 (0.42) | MAPTSMN1; SMN2APPGAAGLO1 | |
| SCHEMBL6272311 | 0.67 | CYP1A2 (0.32) | GAACYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL6324975 | 0.67 | SMN1; SMN2 (0.40) | MAPTSMN1; SMN2APPGAAGLO1 | |
| SCHEMBL6322972 | 0.66 | SLC22A3 (0.37) | GAAALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL6321015 | 0.65 | CYP1A2 (0.34) | GAACYP2C9CYP2C19CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143349-A1 | Phosphorus containing compounds useful for the regulation of LDL and Lp(a) levels | QUATRX PHARMACEUTICALS CO. | 2005-06-30 | — | — | US | claimed |
| US-20050143349-A1 | Phosphorus containing compounds useful for the regulation of LDL and Lp(a) levels | QUATRX PHARMACEUTICALS CO. | 2005-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143349-A1 | Phosphorus containing compounds useful for the regulation of LDL and Lp(a) levels | APOB, LDLR, LPL | MAPT 4686/4885SMN1; SMN2 4738/4885APP 374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.