Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6321835 | 1.00 | PTPN5 (0.46) | PTPN5KDM4ERXFP1PSMD14RECQL | |
| SCHEMBL6320006 | 0.90 | MEN1 (0.45) | PTPN5KDM4ERXFP1PSMD14RECQL | |
| SCHEMBL6322504 | 0.90 | MEN1 (0.45) | PTPN5KDM4ERXFP1PSMD14RECQL | |
| SCHEMBL6320931 | 0.85 | PTPN5 (0.50) | PTPN5KDM4ERXFP1PSMD14RECQL | |
| SCHEMBL6319291 | 0.85 | PTPN5 (0.50) | PTPN5KDM4ERXFP1PSMD14RECQL | |
| SCHEMBL6321853 | 0.85 | PPARG (0.42) | PTPN5KDM4ERXFP1PSMD14RECQL | |
| SCHEMBL6321859 | 0.85 | PPARG (0.42) | PTPN5KDM4ERXFP1PSMD14RECQL | |
| SCHEMBL6320717 | 0.84 | PTGS2 (0.38) | TDP1ALDH1A1GAAMAPTPTGS2 | |
| SCHEMBL6320714 | 0.84 | PTGS2 (0.38) | TDP1ALDH1A1GAAMAPTPTGS2 | |
| SCHEMBL6318590 | 0.80 | PTPN5 (0.48) | PTPN5KDM4ERXFP1PSMD14RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171185-A1 | Indole derivatives | FUJISAWA PHARMACEUTICAL CO., LTD., A JAPANESE CORPORATION | 2005-08-04 | — | — | US | disclosed |
| CN-1150167-C | Indole derivatives | ����ҩƷ��ҵ��ʽ���� | 2004-05-19 | — | — | CN | disclosed |
| CN-1303371-A | Indole derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-07-11 | — | — | CN | disclosed |
| EP-1070705-A1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-01-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171185-A1 | Indole derivatives | PDE5A, IGFBP5, HTR5A | PTPN5 108/4885KDM4E 942/4885RXFP1 500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.