⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL930755 | 0.72 | GABRA1 (0.48) | — | |
| SCHEMBL930890 | 0.68 | TSHR (0.53) | — | |
| SCHEMBL5074476 | 0.67 | MEN1 (0.36) | — | |
| SCHEMBL127281 | 0.65 | — | — | |
| SCHEMBL2195862 | 0.64 | TYR (0.50) | — | |
| SCHEMBL11157268 | 0.64 | — | — | |
| SCHEMBL21268168 | 0.64 | — | — | |
| SCHEMBL5822189 | 0.60 | GABRA1 (0.50) | — | |
| SCHEMBL5366216 | 0.60 | GABRA1 (0.48) | — | |
| SCHEMBL2998047 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6855711-B1 | Pharmaceutical compositions comprising iron chelators for the treatment of neurodegenerative disorders and some novel iron chelators | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2005-02-15 | — | — | US | claimed |
| US-6855711-B1 | Pharmaceutical compositions comprising iron chelators for the treatment of neurodegenerative disorders and some novel iron chelators | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2005-02-15 | — | — | US | disclosed |
| EP-1189606-A2 | NOVEL IRON CHELATORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING IRON CHELATORS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | YEDA RESEARCH AND DEVELOPMENT Co. LTD. (IL) | 2002-03-27 | — | — | EP | disclosed |
| WO-2000074664-A2 | NOVEL IRON CHELATORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING IRON CHELATORS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2000-12-14 | — | — | WO | disclosed |