Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 7/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5366216 | 0.82 | GABRA1 (0.48) | GABRA1GABRB2GABRB1LMNASLC6A2 | |
| SCHEMBL930890 | 0.81 | TSHR (0.53) | GABRA1GABRB2TSHRHPGDHSP90AA1 | |
| SCHEMBL5074476 | 0.79 | MEN1 (0.36) | GABRA1GABRB2TSHR | |
| SCHEMBL698305 | 0.78 | GABRA1 (0.33) | GABRA1GABRB2GABRB1LMNASLC6A2 | |
| SCHEMBL2195862 | 0.77 | TYR (0.50) | GABRA1GABRB2LMNATSHRPTGS1 | |
| SCHEMBL10887452 | 0.76 | LMNA (0.32) | GABRA1GABRB2GABRB1LMNASLC6A2 | |
| SCHEMBL3090389 | 0.73 | LMNA (0.32) | GABRA1GABRB2GABRB1LMNASLC6A2 | |
| SCHEMBL2267523 | 0.73 | FAAH (0.30) | GABRA1GABRB2GABRB1LMNASLC6A2 | |
| SCHEMBL1651125 | 0.73 | GABRA1 (0.32) | GABRA1GABRB2GABRB1LMNASLC6A2 | |
| SCHEMBL27844320 | 0.73 | FAAH (0.30) | GABRA1GABRB2GABRB1LMNASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107750264-A | Rubber composition containing main chain benzoxazine and preparation method thereof | 可隆工业株式会社 | 2018-03-02 | — | — | CN | claimed |
| CN-103408442-A | Aromatic diamine monomer containing bis(trifluoromethyl), bisisopropyl and fluorenyl structures simultaneously, and preparation method and application thereof | UNIV CHANGZHOU | 2013-11-27 | — | — | CN | claimed |
| US-7271183-B2 | 2-Piperidone derivatives as prostaglandin agonists | ROCHE PALO ALTO LLC (US) | 2007-09-18 | — | — | US | claimed |
| CN-113785023-B | Water-based ink composition for reversible thermochromic writing instrument, refill for refill and water-based ballpoint pen incorporating same | 株式会社百乐 | 2023-05-12 | — | — | CN | disclosed |
| CN-113785023-A | Water-based ink composition for reversible thermal discoloration writing instrument, refill containing the same, and water-based ballpoint pen | 株式会社百乐 | 2021-12-10 | — | — | CN | disclosed |
| CN-108350159-B | Method for producing resin composition | 三菱瓦斯化学株式会社 | 2021-09-21 | — | — | CN | disclosed |
| CN-109593196-B | Resin produced by polycondensation and resin composition | 三菱瓦斯化学株式会社 | 2021-08-13 | — | — | CN | disclosed |
| CN-108350262-B | Resin composition, and optical lens, sheet and film each comprising same | 三菱瓦斯化学株式会社 | 2021-07-30 | — | — | CN | disclosed |
| CN-108350161-B | Polycarbonate resin | 三菱瓦斯化学株式会社 | 2020-06-16 | — | — | CN | disclosed |
| CN-109562944-A | hard mask composition | 亚历克斯·菲利普·格雷厄姆·罗宾逊 | 2019-04-02 | — | — | CN | disclosed |
| CN-107207889-A | For making the polyester dispersants that ceramic tile is coloured using ink jet type ink and ink-jet printer | 路博润先进材料公司 | 2017-09-26 | — | — | CN | disclosed |
| US-20100016633-A1 | such as bis(3-formyl-4-(4-methoxycarbonylphenyl)methoxyphenyl)methane, by reacting bis(hydroxymethyl-hydroxyphenyl)alkane with hexamethylene tetramine in presence of acid and hydrolyzing, then reacting with halogenated alkoxycarbonyl hydrocarbon in presence of base | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-01-21 | — | — | US | disclosed |
| CN-101119747-A | Tissue factor production inhibitor | SANKYO CO (JP) | 2008-02-06 | — | — | CN | disclosed |
| CN-1930006-A | Developer mixture for thermal recording materials and thermal recording materials | API CORP (JP) | 2007-03-14 | — | — | CN | disclosed |
| US-4806675-A | CATALYTIC ESTERIFICATION WITH HYDROXYALKANOIC AND THIOALKANOIC ACIDS; HEAT AND OXIDATION RESISTANCE | MALLINCKRODT, INC. (US) | 1989-02-21 | — | — | US | disclosed |
| US-4794138-A | STABILIZERS OF ORGANIC MATERIAL NORMALLY SUSCEPTIBLE TO OXIDATIVE AND/OR THERMAL DETERIORATION | MALLINCKRODT, INC. (US) | 1988-12-27 | — | — | US | disclosed |
| US-4772741-A | STABILIZERS FOR POLYMERS | MILLINCKRODT, INC. (US) | 1988-09-20 | — | — | US | disclosed |
| US-4734519-A | STABILIZERS | MALLINCKRODT, INC. (US) | 1988-03-29 | — | — | US | disclosed |
| EP-0250087-A1 | Pentaerythritol co-esters | MALLINCKRODT, INC. (US) | 1987-12-23 | — | — | EP | disclosed |
| US-4098760-A | NON-MIGRATORY, NON-LEACHING | UNIROYAL, INC. (US) | 1978-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016633-A1 | such as bis(3-formyl-4-(4-methoxycarbonylphenyl)methoxyphenyl)methane, by reacting bis(hydroxymethyl-hydroxyphenyl)alkane with hexamethylene tetramine in presence of acid and hydrolyzing, then reacting with halogenated alkoxycarbonyl hydrocarbon in presence of base | PAH, PGM2, HNMT | GABRA1 3928/4885GABRB2 4543/4885GABRB1 4489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.