SCHEMBL930890

SCHEMBL930890

CCC(C)c1c[c]ccc1O

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.53
RORC P51449 1/20 0.44
USP2 O75604 1/20 0.38
ALDH1A1 P00352 1/20 0.38
GAA P10253 1/20 0.38
PKM P14618 1/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
HSD17B10 Q99714 1/20 0.38
HDAC4 P56524 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
GABRA1 P14867 1/20 0.34
GABRB2 P47870 1/20 0.34
THRA P10827 1/20 0.33
THRB P10828 1/20 0.33
HSP90AA1 P07900 3/20 0.31
HSP90AB1 P08238 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17134304 0.83 TSHR (0.42) TSHRRORC
SCHEMBL10887031 0.82 TSHR (0.41) TSHRRORC
SCHEMBL930755 0.81 GABRA1 (0.48) TSHRHPGDGABRA1GABRB2HSP90AA1
SCHEMBL17262569 0.78 TSHR (0.38) TSHRRORC
SCHEMBL8766765 0.77 TSHR (0.48) TSHRRORCUSP2ALDH1A1GAA
SCHEMBL27768746 0.74 TSHR (0.38) TSHRRORC
SCHEMBL5074476 0.74 MEN1 (0.36) TSHRGABRA1GABRB2
SCHEMBL2195862 0.72 TYR (0.50) TSHRALDH1A1HPGDHSD17B10GABRA1
SCHEMBL11619813 0.72 TSHR (0.36) TSHRRORCALDH1A1
SCHEMBL7862421 0.71 LMNA (0.36) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009131692-A1 SUBSTRATES FOR DELIVERY OF PHYSIOLOGICALLY ACTIVE AGENTS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) 2009-10-29 WO claimed
CN-105051109-B Polymer compositions, methods of manufacture, and articles formed therefrom 沙特基础全球技术有限公司 2017-04-19 CN disclosed
US-9522868-B2 Tetrakis(ether-substituted formylphenyl) HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2016-12-20 US disclosed
CN-106029778-A Thermoplastic composition and article SABIC环球技术有限责任公司 2016-10-12 CN disclosed
CN-105960389-A Method for producing carbonates 沙特基础工业全球技术有限公司 2016-09-21 CN disclosed
CN-103270120-B The manufacture method of coatings, insulated electric conductor and insulated electric conductor 古河电气工业株式会社 2016-06-22 CN disclosed
US-20160016884-A1 NEW TETRAKIS(ETHER-SUBSTITUTED FORMYLPHENYL) HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2016-01-21 US disclosed
US-8921613-B2 Polynuclear poly(phenol) family HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2014-12-30 US disclosed
US-8563770-B2 Bis(formylphenyl) compound and novel polynuclear polyphenol compound derived from the same HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2013-10-22 US disclosed
CN-103270120-A Insulating coating material, insulated wire, and method for producing insulated wire FURUKAWA ELECTRIC CO LTD 2013-08-28 CN disclosed
EP-0977549-A1 PERFUMES HAVING ODOR LONGEVITY BENEFITS THE PROCTER & GAMBLE COMPANY (US) 2000-02-09 EP disclosed
EP-0977548-A1 FRAGRANCE PRO-ACCORDS THE PROCTER & GAMBLE COMPANY (US) 2000-02-09 EP disclosed
EP-0918835-A1 RINSE ADDED FABRIC SOFTENING COMPOSITIONS AND METHOD OF USE FOR THE DELIVERY OF FRAGRANCE PRECURSORS THE PROCTER & GAMBLE COMPANY (US) 1999-06-02 EP disclosed
WO-1999000347-A1 PRO-FRAGRANCE LINEAR ACETALS AND KETALS THE PROCTER & GAMBLE COMPANY (US) 1999-01-07 WO disclosed
WO-1998047996-A1 LAUNDRY DETERGENT COMPOSITIONS COMPRISING FRAGRANCE PRO-ACCORDS THE PROCTER & GAMBLE COMPANY (US) 1998-10-29 WO disclosed
WO-1998047477-A1 FRAGRANCE PRO-ACCORDS THE PROCTER & GAMBLE COMPANY (US) 1998-10-29 WO disclosed
WO-1998047478-A1 PERFUMES HAVING ODOR LONGEVITY BENEFITS THE PROCTER & GAMBLE COMPANY (US) 1998-10-29 WO disclosed
WO-1998006803-A1 RINSE ADDED FABRIC SOFTENING COMPOSITIONS AND METHOD OF USE FOR THE DELIVERY OF FRAGRANCE PRECURSORS THE PROCTER & GAMBLE COMPANY (US) 1998-02-19 WO disclosed
US-4173630-A N2 Arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1979-11-06 US disclosed
US-4098760-A NON-MIGRATORY, NON-LEACHING UNIROYAL, INC. (US) 1978-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160016884-A1 NEW TETRAKIS(ETHER-SUBSTITUTED FORMYLPHENYL) AHR, PAH, ALK TSHR 820/4885RORC 442/4885USP2 3982/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.