SCHEMBL6321981

SCHEMBL6321981

COC(=O)c1cccc(NC(=O)NS(=O)(=O)c2ccc(C)cc2)c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TCF4 P15884 2/20 0.73
CTNNB1 P35222 2/20 0.73
LMNA P02545 1/20 0.65
KMT2A Q03164 4/20 0.58
MEN1 O00255 3/20 0.58
GPR17 Q13304 1/20 0.57
TP53 P04637 1/20 0.55
CA12 O43570 1/20 0.55
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
CA4 P22748 1/20 0.55
CA6 P23280 1/20 0.55
CA5A P35218 1/20 0.55
CA7 P43166 1/20 0.55
CA9 Q16790 1/20 0.55
CA13 Q8N1Q1 1/20 0.55
CA14 Q9ULX7 1/20 0.55
RAB9A P51151 5/20 0.54
NPC1 O15118 3/20 0.54
MAPT P10636 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6326710 0.90 RAB9A (0.62) TCF4CTNNB1LMNAKMT2AMEN1
SCHEMBL7602126 0.89 LMNA (0.61) TCF4CTNNB1LMNAKMT2AMEN1
SCHEMBL1928909 0.89 LMNA (0.61) TCF4CTNNB1LMNAKMT2AMEN1
SCHEMBL6330701 0.89 TP53 (0.64) TCF4CTNNB1LMNAKMT2AMEN1
SCHEMBL6323586 0.89 GPR17 (0.62) TCF4CTNNB1KMT2AMEN1GPR17
SCHEMBL8418023 0.88 LMNA (0.70) TCF4CTNNB1LMNAKMT2AMEN1
SCHEMBL1929671 0.87 LMNA (0.58) TCF4CTNNB1LMNAKMT2AMEN1
SCHEMBL7595935 0.87 LMNA (0.65) TCF4CTNNB1LMNAKMT2AMEN1
SCHEMBL1929599 0.87 LMNA (0.58) TCF4CTNNB1LMNAKMT2AMEN1
SCHEMBL6463046 0.87 LMNA (0.72) TCF4CTNNB1LMNAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6858565-B2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2005-02-22 US disclosed
US-20030040434-A1 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2003-02-27 US disclosed
EP-1264707-A2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2002-12-11 EP disclosed