SCHEMBL6326710

SCHEMBL6326710

COC(=O)c1cccc(NC(=O)NS(=O)(=O)c2ccccc2)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 7/20 0.62
TCF4 P15884 2/20 0.57
CTNNB1 P35222 2/20 0.57
LMNA P02545 1/20 0.57
NPC1 O15118 5/20 0.56
MAPT P10636 3/20 0.56
MEN1 O00255 3/20 0.56
KMT2A Q03164 3/20 0.56
CYP1A2 P05177 1/20 0.55
CYP3A4 P08684 1/20 0.55
CYP2D6 P10635 1/20 0.55
CYP2C9 P11712 1/20 0.55
CYP2C19 P33261 1/20 0.55
CASR P41180 1/20 0.55
POLB P06746 2/20 0.55
ALDH1A1 P00352 2/20 0.53
HPGD P15428 1/20 0.53
GPR17 Q13304 1/20 0.53
PKM P14618 1/20 0.53
NPSR1 Q6W5P4 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6321981 0.90 TCF4 (0.73) RAB9ATCF4CTNNB1LMNANPC1
SCHEMBL6323586 0.89 GPR17 (0.62) RAB9ATCF4CTNNB1NPC1MAPT
SCHEMBL6324678 0.88 SMN1; SMN2 (0.60) RAB9ALMNANPC1MAPTMEN1
SCHEMBL6322969 0.86 ALDH1A1 (0.59) RAB9ALMNANPC1MAPTMEN1
SCHEMBL6324425 0.84 LMNA (0.56) LMNAMAPTMEN1KMT2ACYP2C9
SCHEMBL6324438 0.84 IDH1 (0.60) RAB9ATCF4CTNNB1NPC1MAPT
SCHEMBL8369354 0.83 TCF4 (0.80) RAB9ATCF4CTNNB1LMNAMEN1
SCHEMBL7595935 0.82 LMNA (0.65) RAB9ATCF4CTNNB1LMNANPC1
SCHEMBL6324642 0.82 MEN1 (0.54) RAB9ALMNANPC1MAPTMEN1
SCHEMBL6326485 0.82 MEN1 (0.54) RAB9ALMNANPC1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6858565-B2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2005-02-22 US disclosed
US-20030040434-A1 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2003-02-27 US disclosed
EP-1264707-A2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2002-12-11 EP disclosed