Sugi Predict

Sugi Predict / Compounds / SCHEMBL6322219

SCHEMBL6322219

SCHEMBL6322219

CCC1(C)CC(NC(=O)C2CC=CCC2)C(C)C(C)(CC)N1OC(C)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 1/20 0.34
▸ RAB9A P51151 1/20 0.32
▸ MEN1 O00255 2/20 0.30
▸ ALDH1A1 P00352 2/20 0.30
▸ KMT2A Q03164 2/20 0.30
▸ MAPT P10636 1/20 0.30
▸ ALOX15 P16050 1/20 0.30
▸ HTT P42858 1/20 0.30
▸ ESR2 Q92731 1/20 0.30
▸ HSD17B10 Q99714 1/20 0.30
▸ CYP3A4 P08684 2/20 0.30
▸ CYP2C9 P11712 2/20 0.30
▸ TSHR P16473 2/20 0.30
▸ LMNA P02545 1/20 0.30
▸ CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6328975 0.88 RECQL (0.37) RAB9AMEN1ALDH1A1KMT2ATSHR
SCHEMBL5337732 0.84 KDM4E (0.32) MEN1ALDH1A1KMT2ACYP3A4
SCHEMBL5349603 0.84 TACR1 (0.36) MEN1ALDH1A1KMT2AMAPTHTT
SCHEMBL7108040 0.83 HTT (0.32) MEN1ALDH1A1KMT2AHTTHSD17B10
SCHEMBL5342912 0.83 TACR1 (0.35) RAB9AMEN1ALDH1A1KMT2AHTT
SCHEMBL5346055 0.83 KMT2A (0.32) MEN1ALDH1A1KMT2AHTTHSD17B10
SCHEMBL5338461 0.83 CYP3A4 (0.35) MEN1ALDH1A1KMT2AMAPTHTT
SCHEMBL7106979 0.82 CYP3A4 (0.36) MEN1ALDH1A1KMT2AMAPTHTT
SCHEMBL5353842 0.82 TDP1 (0.38) TDP1MEN1ALDH1A1KMT2ACYP3A4
SCHEMBL5345375 0.81 KDM1A (0.34) MEN1ALDH1A1KMT2AMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030065184-A1 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides CIBA SPECIALTY CHEMICALS CORP. 2003-04-03 — — US claimed
US-7160966-B2 2,2,6,6 Diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides CIBA SPECIALTY CHEMICALS CORP. (US) 2007-01-09 — — US disclosed
US-7160966-B2 2,2,6,6 Diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides CIBA SPECIALTY CHEMICALS CORP. (US) 2007-01-09 — — US disclosed
US-20050143539-A1 2,2,6,6 Diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides NESVADBA PETER (CH) 2005-06-30 — — US disclosed
US-6624306-B2 Stabilizer for addition polymer CIBA SPECIALTY CHEMICALS CORPORATION 2003-09-23 — — US disclosed
US-20030065184-A1 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides CIBA SPECIALTY CHEMICALS CORP. 2003-04-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050143539-A1 2,2,6,6 Diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides ALKBH2, NFE2L2, DPYSL2 TDP1 1454/4885RAB9A 4335/4885MEN1 4443/4885
US-20030065184-A1 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides ALKBH2, NFE2L2, DPYSL2 TDP1 1454/4885RAB9A 4335/4885MEN1 4443/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.