Sugi Predict

Sugi Predict / Compounds / SCHEMBL6328975

SCHEMBL6328975

SCHEMBL6328975

CCC1(C)CC(NC(=O)C2CCCCC2)C(C)C(C)(CC)N1OC(C)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ RECQL P46063 1/20 0.37
▸ LMNA P02545 3/20 0.36
▸ KMT2A Q03164 3/20 0.35
▸ MEN1 O00255 2/20 0.35
▸ SMN1; SMN2 Q16637 4/20 0.35
▸ NPC1 O15118 2/20 0.35
▸ RAB9A P51151 2/20 0.35
▸ PKM P14618 1/20 0.35
▸ EPHX2 P34913 1/20 0.35
▸ POLB P06746 1/20 0.35
▸ ALDH1A1 P00352 1/20 0.34
▸ HPGD P15428 1/20 0.34
▸ TSHR P16473 1/20 0.34
▸ CYP2C19 P33261 1/20 0.34
▸ ACKR3 P25106 1/20 0.34
▸ L3MBTL1 Q9Y468 1/20 0.34
▸ DRD2 P14416 1/20 0.33
▸ DRD3 P35462 1/20 0.33
▸ EPHX1 P07099 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5340588 0.88 EPHX1 (0.43) LMNAKMT2AMEN1SMN1; SMN2NPC1
SCHEMBL6322219 0.88 TDP1 (0.34) LMNAKMT2AMEN1RAB9AALDH1A1
SCHEMBL5349603 0.87 TACR1 (0.36) LMNAKMT2AMEN1SMN1; SMN2POLB
SCHEMBL5343252 0.86 LMNA (0.35) LMNAKMT2AMEN1SMN1; SMN2EPHX2
SCHEMBL7108040 0.86 HTT (0.32) LMNAKMT2AMEN1SMN1; SMN2POLB
SCHEMBL5338461 0.86 CYP3A4 (0.35) LMNAKMT2AMEN1SMN1; SMN2POLB
SCHEMBL5342912 0.86 TACR1 (0.35) LMNAKMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL5346055 0.86 KMT2A (0.32) LMNAKMT2AMEN1SMN1; SMN2POLB
SCHEMBL5353842 0.85 TDP1 (0.38) KMT2AMEN1ALDH1A1TSHRCYP2C19
SCHEMBL7106979 0.85 CYP3A4 (0.36) LMNAKMT2AMEN1SMN1; SMN2EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030065184-A1 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides CIBA SPECIALTY CHEMICALS CORP. 2003-04-03 — — US claimed
US-7160966-B2 2,2,6,6 Diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides CIBA SPECIALTY CHEMICALS CORP. (US) 2007-01-09 — — US disclosed
US-7160966-B2 2,2,6,6 Diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides CIBA SPECIALTY CHEMICALS CORP. (US) 2007-01-09 — — US disclosed
US-20050143539-A1 2,2,6,6 Diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides NESVADBA PETER (CH) 2005-06-30 — — US disclosed
US-6624306-B2 Stabilizer for addition polymer CIBA SPECIALTY CHEMICALS CORPORATION 2003-09-23 — — US disclosed
US-20030065184-A1 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides CIBA SPECIALTY CHEMICALS CORP. 2003-04-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050143539-A1 2,2,6,6 Diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides ALKBH2, NFE2L2, DPYSL2 RECQL 4245/4885LMNA 1407/4885KMT2A 1595/4885
US-20030065184-A1 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides ALKBH2, NFE2L2, DPYSL2 RECQL 4245/4885LMNA 1407/4885KMT2A 1595/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.