SCHEMBL6322288

SCHEMBL6322288

O=C(O)Cc1ccc(CC(=O)O)c2c1CC2

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 4/20 0.48
TDP1 Q9NUW8 1/20 0.42
SRC P12931 1/20 0.41
CYP1A2 P05177 2/20 0.40
KDM4E B2RXH2 1/20 0.39
MAPT P10636 1/20 0.39
CAMK2A Q9UQM7 2/20 0.39
CA2 P00918 1/20 0.39
HSD17B10 Q99714 1/20 0.37
DUSP3 P51452 1/20 0.37
PTPN5 P54829 1/20 0.37
PTPN11 Q06124 1/20 0.37
CTDSP1 Q9GZU7 1/20 0.37
BCAT2 O15382 1/20 0.37
ABCC4 O15439 1/20 0.37
LMNA P02545 1/20 0.37
GAA P10253 1/20 0.37
TSHR P16473 1/20 0.37
PTGS1 P23219 1/20 0.37
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14712041 0.76 HSD17B10 (0.51) TDP1KDM4EHSD17B10LMNAGAA
SCHEMBL31321883 0.76 KDM4E (0.41) AKR1B1TDP1SRCCYP1A2KDM4E
SCHEMBL8004072 0.75 ALDH1A1 (0.54) AKR1B1TDP1CYP1A2KDM4EMAPT
SCHEMBL4067407 0.74 AKR1B1 (0.58) AKR1B1TDP1SRCCYP1A2KDM4E
SCHEMBL31321836 0.73 KDM4E (0.61) AKR1B1TDP1KDM4ECA2HSD17B10
SCHEMBL8055673 0.72 AKR1B1 (0.45) AKR1B1TDP1CYP1A2KDM4EMAPT
SCHEMBL28739318 0.72 RXRB (0.55) AKR1B1TDP1LMNARXRARXRB
SCHEMBL3408719 0.72 RXRB (0.55) AKR1B1TDP1KDM4ELMNARXRA
SCHEMBL11741944 0.72 SRC (0.52) AKR1B1TDP1SRCCYP1A2KDM4E
SCHEMBL31321813 0.71 HTR2A (0.34) AKR1B1TDP1SRCHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6895206-B2 Image fixing apparatus and image fixing method for a crystalline resin-containing toner FUJI XEROX COMPANY, LIMITED (JP) 2005-05-17 US disclosed
US-6895205-B2 Mixture of colored toner in crystal structure polymer; heating, pressurization; electrophotography FUJI XEROX CO., LTD. (JP) 2005-05-17 US disclosed
US-20040037596-A1 Image fixing apparatus and image fixing method FUJI XEROX CO., LTD. (JP) 2004-02-26 US disclosed
US-20040022562-A1 Image fixing apparatus and image fixing method FUJI XEROX CO., LTD. (JP) 2004-02-05 US disclosed