Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3771923 | 0.79 | CYP3A4 (0.46) | TSHRALDH1A1CYP3A4CA2PLA2G2C | |
| SCHEMBL3771919 | 0.79 | CYP3A4 (0.46) | TSHRALDH1A1CYP3A4CA2PLA2G2C | |
| SCHEMBL6422458 | 0.78 | AKR1B1 (0.44) | TSHRALDH1A1PLA2G2CTDP1HDAC11 | |
| SCHEMBL2199118 | 0.78 | AKR1B1 (0.44) | TSHRALDH1A1PLA2G2CTDP1HDAC11 | |
| SCHEMBL6312150 | 0.77 | GPR84 (0.46) | TSHRALDH1A1PLA2G2CTDP1HDAC11 | |
| SCHEMBL6312846 | 0.76 | GABRP (0.39) | PLA2G2CHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL9210281 | 0.75 | CA2 (0.50) | TSHRALDH1A1CYP3A4CA2PLA2G2C | |
| SCHEMBL3505247 | 0.75 | CA2 (0.68) | TSHRALDH1A1CYP3A4CA2ATM | |
| SCHEMBL180777 | 0.75 | CA2 (0.68) | TSHRALDH1A1CYP3A4CA2ATM | |
| SCHEMBL9719720 | 0.73 | TSHR (0.60) | TSHRALDH1A1CYP3A4CA2PLA2G2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1515684-A2 | CARE AND/OR MAKE-UP COSMETIC COMPOSITION STRUCTURED WITH SILICONE POLYMERS AND ORGANOGELLING AGENTS, IN RIGID FORM | L'OREAL (FR) | 2005-03-23 | — | — | EP | claimed |
| WO-2003105788-A2 | CARE AND/OR MAKE-UP COSMETIC COMPOSITION STRUCTURED WITH SILICONE POLYMERS AND ORGANOGELLING AGENTS, IN RIGID FORM | L'OREAL (FR) | 2003-12-24 | — | — | WO | claimed |
| EP-1515684-A2 | CARE AND/OR MAKE-UP COSMETIC COMPOSITION STRUCTURED WITH SILICONE POLYMERS AND ORGANOGELLING AGENTS, IN RIGID FORM | L'OREAL (FR) | 2005-03-23 | — | — | EP | disclosed |
| WO-2003105788-A2 | CARE AND/OR MAKE-UP COSMETIC COMPOSITION STRUCTURED WITH SILICONE POLYMERS AND ORGANOGELLING AGENTS, IN RIGID FORM | L'OREAL (FR) | 2003-12-24 | — | — | WO | disclosed |