Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | MGLL | Q99685 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5090793 | 1.00 | TSHR (0.61) | TSHRGAAPLA2G4BLMNAALDH1A1 | |
| SCHEMBL6071806 | 0.86 | MAPT (0.69) | TSHRGAAPLA2G4BLMNAALDH1A1 | |
| SCHEMBL9123718 | 0.85 | MGLL (0.52) | TSHRGAAPLA2G4BLMNAALDH1A1 | |
| SCHEMBL28335565 | 0.83 | LMNA (0.69) | TSHRGAALMNAALDH1A1MAPT | |
| SCHEMBL588999 | 0.83 | ABCB1 (0.63) | TSHRPLA2G4BLMNAALDH1A1S1PR1 | |
| SCHEMBL588614 | 0.83 | ABCB1 (0.63) | TSHRPLA2G4BLMNAALDH1A1S1PR1 | |
| SCHEMBL6836270 | 0.83 | ABCB1 (0.63) | TSHRPLA2G4BLMNAALDH1A1S1PR1 | |
| SCHEMBL27870163 | 0.83 | ABCB1 (0.63) | TSHRPLA2G4BLMNAALDH1A1S1PR1 | |
| SCHEMBL258672 | 0.83 | ABCB1 (0.63) | TSHRPLA2G4BLMNAALDH1A1S1PR1 | |
| Methylparaben SCHEMBL8669426 | 0.82 | CA1 (0.59) | TSHRGAALMNAALDH1A1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884842-B2 | Molecular compounds having complementary surfaces to targets | ALNIS BIOSCIENCES, INC. (US) | 2005-04-26 | — | — | US | disclosed |
| US-20030153001-A1 | Molecular compounds having complementary surfaces to targets | ALNIS, LLC | 2003-08-14 | — | — | US | disclosed |
| EP-1025066-A2 | MOLECULAR COMPOUNDS HAVING COMPLEMENTARY SURFACES TO TARGETS | Alnis, LLC (US) | 2000-08-09 | — | — | EP | disclosed |
| WO-1999019276-A2 | MOLECULAR COMPOUNDS HAVING COMPLEMENTARY SURFACES TO TARGETS | ALNIS, LLC (US) | 1999-04-22 | — | — | WO | disclosed |