Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | MMP1 | P03956 | 2/20 | 0.51 |
| ▸ | MMP13 | P45452 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18359069 | 0.92 | MMP1 (0.57) | CA2CA12CA9MMP1MMP13 | |
| SCHEMBL28852989 | 0.89 | MMP1 (0.49) | CA2CA12CA9MMP1MMP13 | |
| SCHEMBL13897010 | 0.88 | GAA (0.50) | CA2CA12CA9MMP1MMP13 | |
| SCHEMBL21790170 | 0.86 | MMP1 (0.51) | CA2CA12CA9MMP1MMP13 | |
| SCHEMBL13706033 | 0.84 | MMP1 (0.50) | CA2CA12CA9MMP1MMP13 | |
| SCHEMBL19201578 | 0.84 | MMP1 (0.50) | CA2MMP1MMP13ALDH1A1MAPT | |
| SCHEMBL2448076 | 0.83 | MMP1 (0.51) | MMP1MMP13GAAALDH1A1CYP2C9 | |
| SCHEMBL4712813 | 0.81 | CA2 (0.54) | CA2CA12CA9MMP1MMP13 | |
| SCHEMBL23106681 | 0.79 | CA2 (0.57) | CA2CA12CA9MMP1MMP13 | |
| SCHEMBL15948905 | 0.79 | CA2 (0.57) | CA2CA12CA9MMP1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230312455-A1 | PREPARATION OF SUBSTITUTED ACRYLATE COMPOUND | HUA MEDICINE (SHANGHAI) LTD. (CN) | 2023-10-05 | — | — | US | disclosed |
| US-6884842-B2 | Molecular compounds having complementary surfaces to targets | ALNIS BIOSCIENCES, INC. (US) | 2005-04-26 | — | — | US | disclosed |
| US-20030153001-A1 | Molecular compounds having complementary surfaces to targets | ALNIS, LLC | 2003-08-14 | — | — | US | disclosed |
| EP-1025066-A2 | MOLECULAR COMPOUNDS HAVING COMPLEMENTARY SURFACES TO TARGETS | Alnis, LLC (US) | 2000-08-09 | — | — | EP | disclosed |
| WO-1999019276-A2 | MOLECULAR COMPOUNDS HAVING COMPLEMENTARY SURFACES TO TARGETS | ALNIS, LLC (US) | 1999-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230312455-A1 | PREPARATION OF SUBSTITUTED ACRYLATE COMPOUND | ACR, ADCYAP1R1, GNPAT | CA2 4487/4885CA12 3371/4885CA9 1160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.