Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | GFER | P55789 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14432541 | 0.88 | SLC6A2 (0.46) | POLBSLC6A2SLC6A4ALDH1A1GFER | |
| SCHEMBL3372688 | 0.85 | SLC6A2 (0.46) | POLBSLC6A2SLC6A4ALDH1A1GFER | |
| SCHEMBL11621424 | 0.83 | SLC6A2 (0.48) | POLBSLC6A2SLC6A4ALDH1A1GFER | |
| SCHEMBL22381380 | 0.78 | NPSR1 (0.48) | POLBALDH1A1NOTUMMAPTHTT | |
| SCHEMBL30530526 | 0.78 | MAPT (0.55) | POLBSLC6A2SLC6A4ALDH1A1GFER | |
| SCHEMBL24421765 | 0.75 | SLC6A2 (0.45) | POLBSLC6A2SLC6A4ALDH1A1GFER | |
| SCHEMBL4143391 | 0.75 | GAA (0.55) | POLBSLC6A2SLC6A4ALDH1A1GFER | |
| SCHEMBL14557235 | 0.75 | SLC6A2 (0.45) | POLBSLC6A2SLC6A4ALDH1A1GFER | |
| SCHEMBL7112322 | 0.75 | NOTUM (0.50) | POLBALDH1A1NOTUMHTTSMN1; SMN2 | |
| SCHEMBL3371630 | 0.75 | NOTUM (0.49) | POLBSLC6A2SLC6A4ALDH1A1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050154202-A1 | Substituted aryl amides | MERCK & CO., INC. | 2005-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050154202-A1 | Substituted aryl amides | CNR1, CNR2, FAAH | POLB 2454/4885SLC6A2 1641/4885SLC6A4 2261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.