Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4553227 | 0.90 | NOTUM (0.54) | GAAGFERNOTUMALDH1A1MAPT | |
| SCHEMBL27675111 | 0.88 | GAA (0.56) | GAAGFERNOTUMALDH1A1MAPT | |
| SCHEMBL13802543 | 0.85 | GAA (0.57) | GAAGFERNOTUMALDH1A1MAPT | |
| SCHEMBL3372688 | 0.80 | SLC6A2 (0.46) | GAAGFERNOTUMALDH1A1MAPT | |
| SCHEMBL11621424 | 0.80 | SLC6A2 (0.48) | GAAGFERNOTUMALDH1A1MAPT | |
| SCHEMBL8412252 | 0.80 | ALOX15 (0.51) | GAAALDH1A1MAPTPOLBKDM4E | |
| SCHEMBL31447067 | 0.80 | ALOX15 (0.51) | GAAALDH1A1MAPTPOLBKDM4E | |
| SCHEMBL6262183 | 0.79 | SLC6A2 (0.52) | GAAGFERNOTUMALDH1A1MAPT | |
| SCHEMBL27643466 | 0.79 | NOTUM (0.55) | GAAGFERNOTUMALDH1A1MAPT | |
| SCHEMBL1102007 | 0.78 | ALDH1A1 (0.48) | GAAGFERNOTUMALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478559-B | Solid-state light-stimulated fluorescence rapid color-changing material, and preparation method and application thereof | 吉林大学 | 2023-05-12 | — | — | CN | claimed |
| CN-114478559-A | Solid-state light-stimulated fluorescence rapid color-changing material and preparation method and application thereof | 吉林大学 | 2022-05-13 | — | — | CN | claimed |
| CN-117050089-A | Development method of pure solid novel aromatic heterocyclic spiropyran intelligent color-changing material | 洛阳船舶材料研究所(中国船舶集团有限公司第七二五研究所) | 2023-11-14 | — | — | CN | disclosed |
| CN-114478559-B | Solid-state light-stimulated fluorescence rapid color-changing material, and preparation method and application thereof | 吉林大学 | 2023-05-12 | — | — | CN | disclosed |
| CN-114478559-A | Solid-state light-stimulated fluorescence rapid color-changing material and preparation method and application thereof | 吉林大学 | 2022-05-13 | — | — | CN | disclosed |
| CN-105670389-B | A kind of reversible solid state photochromic fluorescent ink material and its application | 吉林大学 | 2019-02-05 | — | — | CN | disclosed |
| US-8785474-B2 | Vanilloid receptor ligands, pharmaceutical compositions containing them, process for making them, and use thereof to treat pain and other conditions | GRUENENTHAL GMBH (DE) | 2014-07-22 | — | — | US | disclosed |
| US-8084484-B2 | Vanilloid receptor ligands, pharmaceutical compositions containing them, process for making them, and use thereof for treating pain and other conditions | GRUENENTHAL GMBH (DE) | 2011-12-27 | — | — | US | disclosed |
| US-20110301156-A1 | Vanilloid Receptor Ligands, Pharmaceutical Compositions Containing Them, Process For Making Them, and Use Thereof to Treat Pain and Other Conditions | GRUENENTHAL GMBH (DE) | 2011-12-08 | — | — | US | disclosed |
| CN-101679370-A | Novel vanilloid receptor ligands and the use thereof for the production of pharmaceuticals | GRUENENTHAL GMBH | 2010-03-24 | — | — | CN | disclosed |
| US-20090156590-A1 | Vanilloid Receptor Ligands, Pharmaceutical Compositions Containing Them, Process for Making Them, and Use Thereof for Treating Pain and Other Conditions | GRUENENTHAL GMBH (DE) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156590-A1 | Vanilloid Receptor Ligands, Pharmaceutical Compositions Containing Them, Process for Making Them, and Use Thereof for Treating Pain and Other Conditions | TRPV1, OPRL1, TRPV2 | GAA 1817/4885GFER 2055/4885NOTUM 2673/4885 |
| US-20110301156-A1 | Vanilloid Receptor Ligands, Pharmaceutical Compositions Containing Them, Process For Making Them, and Use Thereof to Treat Pain and Other Conditions | TRPV1, OPRL1, TRPV2 | GAA 1794/4885GFER 2038/4885NOTUM 2452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.