Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | RXRA | P19793 | 1/20 | 0.56 |
| ▸ | RXRB | P28702 | 1/20 | 0.56 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.54 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.54 |
| ▸ | STS | P08842 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14446354 | 0.94 | ATM (0.59) | KMT2AMEN1GAAHTTRXRA | |
| SCHEMBL15281240 | 0.87 | KMT2A (0.59) | KMT2AMEN1GAAHTTRXRA | |
| SCHEMBL11798200 | 0.86 | KMT2A (0.64) | KMT2AMEN1GAAHTTRXRA | |
| SCHEMBL592781 | 0.86 | RXRA (0.68) | KMT2AMEN1GAAHTTRXRA | |
| SCHEMBL30184304 | 0.86 | RXRA (0.68) | KMT2AMEN1GAAHTTRXRA | |
| SCHEMBL104194 | 0.86 | KMT2A (0.59) | KMT2AMEN1GAAHTTRXRA | |
| SCHEMBL1167621 | 0.85 | KMT2A (0.58) | KMT2AMEN1GAAHTTRXRA | |
| SCHEMBL2466047 | 0.85 | GABRA1 (0.54) | KMT2AMEN1GAAHTTRXRA | |
| SCHEMBL12667381 | 0.85 | KMT2A (0.58) | KMT2AMEN1GAAHTTRXRA | |
| SCHEMBL12643325 | 0.85 | KMT2A (0.58) | KMT2AMEN1GAAHTTRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |