Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.72 |
| ▸ | HTT | P42858 | 1/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29671913 | 1.00 | MAPT (0.72) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL28989929 | 0.98 | MAPT (0.69) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL2861062 | 0.98 | MAPT (0.69) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| Alcohol SCHEMBL9857028 | 0.94 | MAPT (0.64) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| Phenol SCHEMBL6873397 | 0.87 | MAPT (0.56) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11744399 | 0.87 | MAPT (0.56) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9298116 | 0.86 | MAPT (0.55) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3363357 | 0.85 | MAPT (0.50) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11293767 | 0.84 | HSD17B10 (0.57) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9396667 | 0.84 | MAPT (0.75) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1027 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946370-A | Ester bond curing agent, degradable epoxy resin and preparation of composite material thereof | 四川大学 | 2024-04-30 | — | — | CN | claimed |
| US-20230025076-A1 | TRIARYL METHANE COMPOSITION, DYE COMPOSITION FOR OCULAR MEMBRANE DYEING | D. WESTERN THERAPEUTICS INSTITUTE, INC. (JP) | 2023-01-26 | — | — | US | claimed |
| CN-110590573-B | Preparation method of high-purity N-ethyl-N-hydroxyethyl-m-toluidine | 武汉奥克特种化学有限公司 | 2022-09-23 | — | — | CN | claimed |
| CN-110590574-B | Preparation method of organic intermediate N-ethyl-N-beta-hydroxypropyl m-toluidine | 绍兴君泰纺织科技有限公司 | 2022-08-05 | — | — | CN | claimed |
| CN-113418877-A | Free fatty acid detection kit and method | 东软威特曼生物科技(南京)有限公司 | 2021-09-21 | — | — | CN | claimed |
| CN-110590573-A | Preparation method of high-purity N-ethyl-N-hydroxyethyl-m-toluidine | 武汉奥克特种化学有限公司 | 2019-12-20 | — | — | CN | claimed |
| CN-110590574-A | Preparation method of organic intermediate N-ethyl-N-beta-hydroxypropyl m-toluidine | 绍兴君泰纺织科技有限公司 | 2019-12-20 | — | — | CN | claimed |
| CN-110387144-A | Blue dyestuff of a kind of dispersion and application thereof | 杭州福莱蒽特精细化工有限公司 | 2019-10-29 | — | — | CN | claimed |
| CN-108949900-A | One kind can continuously monitor adenosine deaminase detection kit and preparation method thereof | 金华市强盛生物科技有限公司 | 2018-12-07 | — | — | CN | claimed |
| EP-3381475-A1 | TRIARYLMETHANE COMPOSITION, DYE COMPOSITION FOR OCULAR MEMBRANE DYEING | D. Western Therapeutics Institute, Inc. (JP) | 2018-10-03 | — | — | EP | claimed |
| US-20030105100-A1 | Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | G.D. SEARLE & CO. | 2003-06-05 | — | — | US | claimed |
| US-20030100559-A1 | Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | G.D. SEARLE & CO. | 2003-05-29 | — | — | US | claimed |
| US-20030096818-A1 | Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | G.D. SEARLE & CO. (US) | 2003-05-22 | — | — | US | claimed |
| US-20030087905-A1 | Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | G.D. SEARLE & CO. | 2003-05-08 | — | — | US | claimed |
| US-20030083331-A1 | Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | G.D. SEARLE & CO. (US) | 2003-05-01 | — | — | US | claimed |
| US-20030032644-A1 | Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | G.D. SEARLE & CO. | 2003-02-13 | — | — | US | claimed |
| US-20020165232-A1 | Substituted N, N-disubstituted cycloalkyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity | SIKORSKI JAMES A (US) | 2002-11-07 | — | — | US | claimed |
| US-20020165231-A1 | Substituted N-heteroaryl-N-phenyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity | SIKORSKI JAMES A (US) | 2002-11-07 | — | — | US | claimed |
| US-3973981-A | PHTHALOCYANINE DYES, PAINTS, INKS | TOYO INK MANUFACTURING CO., LTD. (JA) | 1976-08-10 | — | — | US | claimed |
| US-3950287-A | CURING, AMINES, FREE RADICAL CATALYSTS | ASHLAND OIL, INC. (US) | 1976-04-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105100-A1 | Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | CETP, MTTP, LCAT | MAPT 3088/4885CYP1A2 1679/4885CYP3A4 1181/4885 |
| US-20030096818-A1 | Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | CETP, MTTP, LCAT | MAPT 3088/4885CYP1A2 1679/4885CYP3A4 1181/4885 |
| US-20020165231-A1 | Substituted N-heteroaryl-N-phenyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity | CETP, LCAT, MTTP | MAPT 2318/4885CYP1A2 2021/4885CYP3A4 1805/4885 |
| US-20030087905-A1 | Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | CETP, MTTP, LCAT | MAPT 3088/4885CYP1A2 1679/4885CYP3A4 1181/4885 |
| US-20230025076-A1 | TRIARYL METHANE COMPOSITION, DYE COMPOSITION FOR OCULAR MEMBRANE DYEING | MB, ABCB11, NR1H4 | MAPT 1572/4885CYP1A2 232/4885CYP3A4 117/4885 |
| US-20030100559-A1 | Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | CETP, MTTP, LCAT | MAPT 3088/4885CYP1A2 1679/4885CYP3A4 1181/4885 |
| US-20030083331-A1 | Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | CETP, MTTP, LCAT | MAPT 3088/4885CYP1A2 1679/4885CYP3A4 1181/4885 |
| US-20030032644-A1 | Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | CETP, MTTP, PCTP | MAPT 3276/4885CYP1A2 1488/4885CYP3A4 942/4885 |
| US-20020165232-A1 | Substituted N, N-disubstituted cycloalkyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity | CETP, DBI, PLTP | MAPT 3071/4885CYP1A2 3072/4885CYP3A4 2730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.