Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.40 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2087543 | 0.84 | NPC1 (0.47) | MAOBL3MBTL1EGFRPARP15PARP14 | |
| SCHEMBL958298 | 0.82 | NR4A2 (0.49) | MAOBKMT2AGAAEGFRPARP15 | |
| SCHEMBL4096578 | 0.77 | LMNA (0.59) | MEN1KMT2AL3MBTL1GAANPC1 | |
| SCHEMBL2090015 | 0.76 | GSK3B (0.50) | MAOBPARP15PARP14PARP10NPC1 | |
| SCHEMBL2641408 | 0.76 | MEN1 (0.38) | MAOBMEN1KMT2AL3MBTL1GAA | |
| SCHEMBL2086618 | 0.76 | ALDH1A1 (0.40) | MAOBMEN1KMT2AL3MBTL1GAA | |
| SCHEMBL6763543 | 0.76 | ALDH1A1 (0.40) | MAOBMEN1KMT2AL3MBTL1GAA | |
| SCHEMBL2087289 | 0.76 | MAOB (0.70) | MAOBL3MBTL1GAA | |
| SCHEMBL13304061 | 0.76 | MMP1 (0.58) | MEN1KMT2AL3MBTL1MMP1NPC1 | |
| SCHEMBL6322991 | 0.75 | MAOB (0.42) | MAOBMEN1KMT2AGAAEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102151262-A | Compounds for the treatment of metabolic disorders | WELLSTAT THERAPEUTICS CORP | 2011-08-17 | — | — | CN | disclosed |
| CN-102140064-A | Compounds for the treatment of metabolic disorders | WELLSTAT THERAPEUTICS CORP | 2011-08-03 | — | — | CN | disclosed |
| CN-101444496-B | Compounds for the treatment of metabolic disorders | WELLSTAT THERAPEUTICS CORP | 2011-04-13 | — | — | CN | disclosed |
| CN-101444496-A | Compounds for the treatment of metabolic disorders | WELLSTAT THERAPEUTICS CORP (US) | 2009-06-03 | — | — | CN | disclosed |
| CN-1608055-A | Compounds for the treatment of metabolic disorders | WELLSTAT THERAPEUTICS CORP (US) | 2005-04-20 | — | — | CN | disclosed |
| US-6858602-B2 | Compounds for the treatment of metabolic disorders | WELLSTAT THERAPEUTICS CORPORATION (US) | 2005-02-22 | — | — | US | disclosed |