Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | CACNG8 | Q8WXS5 | 2/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.31 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.31 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6318789 | 0.84 | MAP3K11 (0.35) | PDE3BPDE3AGRIA1MAPKAPK2GRIN2B | |
| SCHEMBL6256396 | 0.82 | EPHX2 (0.32) | GRIA1MAPKAPK2GRIN2BCACNG8SMYD3 | |
| SCHEMBL6325348 | 0.82 | GRIA1 (0.32) | PDE3BPDE3AGRIA1MAPKAPK2CACNG8 | |
| SCHEMBL6268096 | 0.81 | GRIA1 (0.33) | GRIA1MAPKAPK2CACNG8 | |
| SCHEMBL6268458 | 0.73 | MAPKAPK2 (0.32) | PDE3BPDE3AMAPKAPK2GRIN2BBMPR1B | |
| SCHEMBL6320199 | 0.73 | PKM (0.31) | PDE3BPDE3AMAPKAPK2 | |
| SCHEMBL6317954 | 0.72 | PKM (0.33) | PDE3BPDE3AGRIA1MAPKAPK2GRIN2B | |
| SCHEMBL6325622 | 0.68 | EPHX2 (0.34) | PDE3BPDE3AGRIA1MAPKAPK2CACNG8 | |
| SCHEMBL6319203 | 0.67 | GRIA1 (0.34) | PDE3BPDE3AGRIA1MAPKAPK2CACNG8 | |
| SCHEMBL6317836 | 0.65 | CRBN (0.35) | PDE3BPDE3AGRIA1MAPKAPK2CACNG8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143349-A1 | Phosphorus containing compounds useful for the regulation of LDL and Lp(a) levels | QUATRX PHARMACEUTICALS CO. | 2005-06-30 | — | — | US | claimed |
| US-20050143349-A1 | Phosphorus containing compounds useful for the regulation of LDL and Lp(a) levels | QUATRX PHARMACEUTICALS CO. | 2005-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143349-A1 | Phosphorus containing compounds useful for the regulation of LDL and Lp(a) levels | APOB, LDLR, LPL | PDE3B 1124/4885PDE3A 1209/4885GRIA1 2013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.