Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | BMP1 | P13497 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | SLC26A6 | Q9BXS9 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6330573 | 0.98 | MMP2 (0.38) | MMP2BMP1KMT2ALMNAMAPT | |
| SCHEMBL4489619 | 0.87 | KMT2A (0.40) | MMP2BMP1KMT2AMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL6328451 | 0.86 | KMT2A (0.40) | MMP2BMP1KMT2AMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL4489615 | 0.86 | KMT2A (0.40) | MMP2BMP1KMT2AMAPTALDH1A1 | |
| SCHEMBL15932098 | 0.84 | MMP2 (0.41) | MMP2BMP1KMT2ALMNAMAPT | |
| SCHEMBL3214456 | 0.81 | KMT2A (0.43) | MMP2BMP1KMT2AALDH1A1MEN1 | |
| SCHEMBL6623419 | 0.81 | MAPK1 (0.44) | MMP2BMP1KMT2ALMNAMAPT | |
| SCHEMBL12002524 | 0.79 | KMT2A (0.40) | MMP2BMP1KMT2ALMNAMAPT | |
| SCHEMBL29110021 | 0.79 | KMT2A (0.40) | MMP2BMP1KMT2AMAPTALDH1A1 | |
| SCHEMBL1934380 | 0.78 | SLC26A6 (0.40) | MMP2BMP1KMT2AALDH1A1SLC26A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11873291-B2 | Quinoline cGAS antagonist compounds | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2024-01-16 | — | — | US | disclosed |
| US-11873291-B2 | Quinoline cGAS antagonist compounds | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2024-01-16 | — | — | US | disclosed |
| WO-2022094012-A1 | MACROCYCLIC UREA OREXIN RECEPTOR AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2022-05-05 | — | — | WO | disclosed |
| US-6951946-B2 | Large scale synthesis of 1,2,4- and 1,3,4-oxadiazole carboxylates | LEXICON PHARMACEUTICALS, INC. (US) | 2005-10-04 | — | — | US | disclosed |
| US-20050154211-A1 | Large scale synthesis of 1,2,4- and 1,3,4- oxadiazole carboxylates | KOLB HARTMUTH C (US) | 2005-07-14 | — | — | US | disclosed |
| US-20040019215-A1 | Large scale synthesis of 1,2,4- and 1,3,4-oxadiazole carboxylates | LEXICON PHARMACEUTICALS, INC. | 2004-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11873291-B2 | Quinoline cGAS antagonist compounds | CGAS, GLS2, GLS | MMP2 4016/4885BMP1 4561/4885KMT2A 4371/4885 |
| US-20050154211-A1 | Large scale synthesis of 1,2,4- and 1,3,4- oxadiazole carboxylates | OXA1L, ODC1, CYP4B1 | MMP2 3190/4885BMP1 1072/4885KMT2A 3220/4885 |
| US-20040019215-A1 | Large scale synthesis of 1,2,4- and 1,3,4-oxadiazole carboxylates | OXA1L, ODC1, CYP4B1 | MMP2 3190/4885BMP1 1072/4885KMT2A 3220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.