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Sugi Predict / Targets / SLC26A6

SLC26A6

Solute carrier family 26 member 6 · Q9BXS9 · SLC26A6 on Sugi Atlas →

1,606 patent compounds predicted against SLC26A6, 557 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL18320759 SCHEMBL18320759 0.47 14/20
SCHEMBL18320719 SCHEMBL18320719 0.46 14/20
SCHEMBL31073621 SCHEMBL31073621 0.65 13/20
SCHEMBL892151 SCHEMBL892151 0.54 12/20
SCHEMBL31073640 SCHEMBL31073640 0.54 12/20
SCHEMBL892287 SCHEMBL892287 0.52 12/20
SCHEMBL20161301 SCHEMBL20161301 0.52 11/20
SCHEMBL18320802 SCHEMBL18320802 0.43 10/20
SCHEMBL4934957 SCHEMBL4934957 0.46 9/20
SCHEMBL27273059 SCHEMBL27273059 0.44 9/20
SCHEMBL5961528 SCHEMBL5961528 0.43 8/20
SCHEMBL18895532 SCHEMBL18895532 0.57 6/20
SCHEMBL30208433 SCHEMBL30208433 0.57 6/20
SCHEMBL892484 SCHEMBL892484 0.55 6/20
SCHEMBL892478 SCHEMBL892478 0.53 6/20
SCHEMBL31194556 SCHEMBL31194556 0.53 6/20
SCHEMBL6602634 SCHEMBL6602634 0.47 6/20
SCHEMBL893135 SCHEMBL893135 0.45 6/20
SCHEMBL892315 SCHEMBL892315 0.54 5/20
SCHEMBL892925 SCHEMBL892925 0.52 5/20

Clinical trials — most relevant to SLC26A6 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Effect of Age on the Renal Clearance of Adefovir PHASE4WITHDRAWN
Applying Proton Pump Inhibitor to Prevent and Treat Acute Fluctuating Hearing Loss in Patients With SLC26A4 Mutation PHASE2/PHASE3UNKNOWN
Gemcitabine With or Without Bevacizumab in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer PHASE3COMPLETED
A Study Comparing CO-1.01 With Gemcitabine as First Line Therapy in Patients With Metastatic Pancreatic Adenocarcinoma (LEAP) PHASE2COMPLETED
Effect of, OAT3, on the Renal Secretion of Cefotaxime PHASE1COMPLETED
Pharmacokinetic Drug-Drug Interaction Study to Identify Biomarkers of Kidney Transporters EARLY_PHASE1COMPLETED
Natural History Study of SLC25A46 Mutation-related Mitochondriopathy nanCOMPLETED
Oxalate and Citrate in Humans - Response to Citrate nanRECRUITING
Oxalate and Citrate nanRECRUITING
Clinical and Genetic Analysis of Enlarged Vestibular Aqueducts nanCOMPLETED
Genotype-phenotype Correlation of SLC26A4 in CI Patients With EVA nanUNKNOWN
SLC13A5 Deficiency Natural History Study - Remote Only nanENROLLING_BY_INVITATION
Hyperlactacidemia in Major Abdominal Surgery and Monocarboxylate Receptors nanUNKNOWN
SLC6A1-NDD Prospective Longitudinal Natural History Study nanNOT_YET_RECRUITING
Effect of SLC01B1 (rs4149956) Polymorphism on the Efficacy and Tolerability of Atorvastatin in Pakistani Population nanCOMPLETED
Demographic, Metabolic, and Genomic Description of Neonates With Severe Hyperbilirubinemia nanCOMPLETED
Bile Acid Effects in Fetal Arrhythmia Study nanUNKNOWN
Phenotypic and Genotypic Studies in Congenital and Early Onset Ataxias nanCOMPLETED
Clinical Phenotypic Characteristics of SC26A4 nanUNKNOWN
Influence of OCTN2 Variants on Carnitine Status and Plasma Triglycerides nanCOMPLETED
ADPKD Alterations in Hepatic Transporter Function nanCOMPLETED
Impact of Genetics on Metformin Pharmacokinetics nanCOMPLETED
Genes-in-Action - Hepcidin Regulation of Iron Supplementation nanCOMPLETED
Cardiovascular Effects of Empagliflozine nanUNKNOWN
Epidemiology of Gout in French Polynesia nanCOMPLETED
Characterization of Dysmorphology in Subjects With Creatine Transporter Deficiency nanRECRUITING
Observational Study of the Impact of Genetic Testing on Healthcare Decisions and Care in Interventional Pain Management nanUNKNOWN
Impact of Polymorphisms of OAT1, OAT3, and OCT2 on Transportation of Potential Nephrotoxic Drugs nanCOMPLETED
Role of the ATP7A Transporter in Ovarian Cancer nanCOMPLETED
Understanding Methotrexate Induced Gastrointestinal Intolerance in Juvenile Idiopathic Arthritis and Childhood Leukemia nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a SLC26A6 binder may also engage these)

ProteinNameSimilarity
Q8CIW6 — 0.997 Q8CIW6 →
P45380 — 0.981 P45380 →
P58735 — 0.980 P58735 →
P58743 — 0.978 P58743 →
G3C7W6 — 0.977 G3C7W6 →
Q9EPH0 — 0.976 Q9EPH0 →
Q7T2C4 — 0.974 Q7T2C4 →
Q5EBI0 — 0.974 Q5EBI0 →
Q86WA9 — 0.974 Q86WA9 →
D7PC76 — 0.973 D7PC76 →
Q99NH7 — 0.973 Q99NH7 →
Q8NG04 — 0.972 Q8NG04 →
Q8BU91 — 0.972 Q8BU91 →
Q80ZD3 — 0.971 Q80ZD3 →
Q9JKQ2 — 0.971 Q9JKQ2 →
SLC26A3 Chloride anion exchanger 0.970 landscape →
A0FKN5 — 0.966 A0FKN5 →
Q58DD2 — 0.966 Q58DD2 →
O35544 — 0.966 O35544 →
Q7LBE3 — 0.965 Q7LBE3 →
Q9N1R2 — 0.965 Q9N1R2 →
O35921 — 0.965 O35921 →
Q9H2B4 — 0.965 Q9H2B4 →
P50443 — 0.964 P50443 →
Q924C9 — 0.962 Q924C9 →
Q69DJ1 — 0.962 Q69DJ1 →
Q28615 — 0.962 Q28615 →
Q62273 — 0.961 Q62273 →
Q65AC2 — 0.961 Q65AC2 →
P48664 — 0.961 P48664 →