SCHEMBL6323709

SCHEMBL6323709

CO[SiH](CC(c1ccccc1)(c1ccccc1)c1ccccc1)OC

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 8/20 0.40
KCNH2 Q12809 1/20 0.40
MAPK1 P28482 1/20 0.38
KCNN4 O15554 3/20 0.36
TAAR1 Q96RJ0 1/20 0.35
ALDH1A1 P00352 1/20 0.35
ALOX15 P16050 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5413472 0.83 MAPK1 (0.38) KIF11KCNH2MAPK1KCNN4TAAR1
SCHEMBL8366810 0.81 TAAR1 (0.48) MAPK1KCNN4TAAR1ALDH1A1ALOX15
SCHEMBL2543699 0.75 CYP2C19 (0.39) KIF11MAPK1KCNN4TAAR1ALDH1A1
SCHEMBL1197506 0.72 KCNN4 (0.32) MAPK1KCNN4
SCHEMBL5421257 0.71 MAPK1 (0.35) KIF11KCNH2MAPK1KCNN4TAAR1
SCHEMBL6324960 0.70 TSHR (0.42) KIF11KCNN4TAAR1ALDH1A1
SCHEMBL5972484 0.70 KIF11 (0.43) KIF11KCNH2MAPK1KCNN4TAAR1
SCHEMBL3644944 0.69 TAAR1 (0.45) KIF11KCNH2MAPK1KCNN4TAAR1
SCHEMBL5415626 0.68 KIF11 (0.36) KIF11KCNH2MAPK1KCNN4TAAR1
SCHEMBL1971090 0.66 KCNN4 (0.48) KIF11MAPK1KCNN4TAAR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050118742-A1 Method for reducing the adhesive properties of MEMS and anti-adhesion-coated device ROBERT BOSCH GMBH (DE) 2005-06-02 US disclosed