SCHEMBL6324960

SCHEMBL6324960

Cl[SiH](Cl)CC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
KIF11 P52732 9/20 0.41
KCNN4 O15554 2/20 0.36
ALDH1A1 P00352 1/20 0.36
CYP1A2 P05177 2/20 0.34
TAAR1 Q96RJ0 1/20 0.34
CYP11B1 P15538 1/20 0.34
CYP11B2 P19099 1/20 0.34
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8397722 0.76 TAAR1 (0.52) TSHRKCNN4ALDH1A1TAAR1CYP2C19
SCHEMBL2100570 0.72 CYP2C19 (0.42) TSHRKIF11KCNN4ALDH1A1TAAR1
SCHEMBL17151091 0.70 TSHR (0.48) TSHRKIF11KCNN4ALDH1A1CYP1A2
SCHEMBL8208883 0.70 TSHR (0.48) TSHRKIF11KCNN4ALDH1A1CYP1A2
SCHEMBL22704276 0.70 KIF11 (0.52) TSHRKIF11KCNN4ALDH1A1CYP1A2
SCHEMBL6323709 0.70 KIF11 (0.40) KIF11KCNN4ALDH1A1TAAR1
SCHEMBL28873040 0.69 KIF11 (0.50) TSHRKIF11KCNN4ALDH1A1CYP1A2
SCHEMBL1149158 0.69 KIF11 (0.64) TSHRKIF11KCNN4ALDH1A1TAAR1
SCHEMBL11602752 0.67 KIF11 (0.54) TSHRKIF11KCNN4ALDH1A1CYP11B1
SCHEMBL766983 0.65 KIF11 (0.46) TSHRKIF11KCNN4ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130153263-A1 INORGANIC NANOFILLER, PARTIAL DISCHARGE RESISTANT ENAMELED WIRE INCLUDING THE SAME, AND PREPARING METHOD OF THE ENAMELED WIRE SEJONG UNIVERSITY INDUSTRY ACADEMY COOPERATION FOUNDATION (KR) 2013-06-20 US claimed
WO-2016047988-A1 SURFACE MODIFIED BORON NITRIDE, COMPOSITION HAVING SAME DISPERSED THEREIN, AND WIRE COATED WITH THE COMPOSITION 세종대학교산학협력단 2016-03-31 WO disclosed
US-8927630-B2 Inorganic nanofiller, partial discharge resistant enameled wire including the same, and preparing method of the enameled wire SEJONG UNIVERSITY INDUSTRY ACADEMY COOPERATION FOUNDATION (KR) 2015-01-06 US disclosed
US-20130153263-A1 INORGANIC NANOFILLER, PARTIAL DISCHARGE RESISTANT ENAMELED WIRE INCLUDING THE SAME, AND PREPARING METHOD OF THE ENAMELED WIRE SEJONG UNIVERSITY INDUSTRY ACADEMY COOPERATION FOUNDATION (KR) 2013-06-20 US disclosed
US-20050118742-A1 Method for reducing the adhesive properties of MEMS and anti-adhesion-coated device ROBERT BOSCH GMBH (DE) 2005-06-02 US disclosed
US-6022987-A Aryl substituted alkylsilanes and a preparation method thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2000-02-08 US disclosed