SCHEMBL2543699

SCHEMBL2543699

CO[SiH](CC(C)(CCl)c1ccccc1)OC

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.39
HIF1A Q16665 1/20 0.39
MAPK1 P28482 1/20 0.36
TAAR1 Q96RJ0 1/20 0.34
ALDH1A1 P00352 1/20 0.34
ALOX15 P16050 1/20 0.34
KCNN4 O15554 1/20 0.32
TSHR P16473 1/20 0.31
KIF11 P52732 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2100570 0.79 CYP2C19 (0.42) CYP2C19HIF1AMAPK1TAAR1ALDH1A1
SCHEMBL8366810 0.77 TAAR1 (0.48) CYP2C19HIF1AMAPK1TAAR1ALDH1A1
SCHEMBL1197506 0.76 KCNN4 (0.32) MAPK1KCNN4
SCHEMBL6323709 0.75 KIF11 (0.40) MAPK1TAAR1ALDH1A1ALOX15KCNN4
SCHEMBL5413472 0.75 MAPK1 (0.38) CYP2C19HIF1AMAPK1TAAR1ALDH1A1
SCHEMBL17710390 0.72 CYP2C19 (0.47) CYP2C19HIF1AMAPK1TAAR1ALDH1A1
SCHEMBL3644944 0.67 TAAR1 (0.45) CYP2C19HIF1AMAPK1TAAR1ALDH1A1
SCHEMBL812875 0.66 CYP2C19 (0.48) CYP2C19HIF1AMAPK1TAAR1ALDH1A1
SCHEMBL1502452 0.65 TAAR1 (0.58) CYP2C19HIF1AMAPK1TAAR1ALDH1A1
SCHEMBL28272853 0.65 TAAR1 (0.46) CYP2C19HIF1AMAPK1TAAR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12554198-B2 Functional hydrogen silsesquioxane resins and the use thereof PIBOND OY (FI) 2026-02-17 US disclosed
US-20250326936-A1 ARTICLES INCLUDING SURFACE COATINGS AND METHODS TO PRODUCE THEM MAXTERIAL INC (US) 2025-10-23 US disclosed
US-12173166-B2 Articles including surface coatings and methods to produce them MAXTERIAL, INC. (US) 2024-12-24 US disclosed
US-20230295827-A1 COATINGS AND COATED SURFACES INCLUDING LOW-SURFACE ENERGY INORGANIC PARTICLES MAXTERIAL INC (US) 2023-09-21 US disclosed
US-11685702-B2 Method for producing arene compounds and arene compounds produced by the same JSI SILICONE CO. (KR) 2023-06-27 US disclosed
US-11542621-B1 Coatings and coated surfaces including low-surface energy inorganic particles MAXTERIAL, INC. (US) 2023-01-03 US disclosed
US-20220162391-A1 Functional hydrogen silsesquioxane resins and the use thereof PIBOND OY (FI) 2022-05-26 US disclosed
US-20220016624-A1 COMPOSITIONS, METHODS AND SYSTEMS FOR SAMPLE PROCESSING 10X GENOMICS, INC. 2022-01-20 US disclosed
EP-3931639-A1 FUNCTIONAL HYDROGEN SILSESQUIOXANE RESINS AND THE USE THEREOF Pibond Oy (FI) 2022-01-05 EP disclosed
US-11046794-B2 Scale inhibitor compositions and methods of using CYTEC INDUSTRIES INC. (US) 2021-06-29 US disclosed
US-20160159660-A1 SILICON CONTAINING POLYMER FLOCCULANTS CYTEC INDUSTRIES INC. (US) 2016-06-09 US disclosed
US-20150191646-A1 FUNCTIONALIZED SILICATE NANOPARTICLE COMPOSITION, REMOVING AND EXFOLIATING ASPHALTENES WITH SAME BAKER HUGHES INCORPORATED (US) 2015-07-09 US disclosed
US-9012377-B2 Functionalized silicate nanoparticle composition, removing and exfoliating asphaltenes with same BAKER HUGHES INCORPORATED (US) 2015-04-21 US disclosed
WO-2014106007-A1 FUNCTIONALIZED SILICATE NANOPARTICLE COMPOSITION, REMOVING AND EXFOLIATING ASPHALTENES WITH SAME BAKER HUGHES INCORPORATED (US) 2014-07-03 WO disclosed
US-20140187449-A1 FUNCTIONALIZED SILICATE NANOPARTICLE COMPOSITION, REMOVING AND EXFOLIATING ASPHALTENES WITH SAME BAKER HUGHES INCORPORATED (US) 2014-07-03 US disclosed
US-8501326-B2 Wax replacement specialty formulated corrugating adhesive HENKEL CORPORATION (US) 2013-08-06 US disclosed
US-20110259945-A1 WAX REPLACEMENT SPECIALTY FORMULATED CORRUGATING ADHESIVE HENKEL AG & CO. KGAA (DE) 2011-10-27 US disclosed
WO-2010080973-A2 WAX REPLACEMENT SPECIALTY FORMULATED CORRUGATING ADHESIVE HENKEL CORPORATION (US) 2010-07-15 WO disclosed
WO-2010054134-A1 WATERBORNE ADHESIVE HENKEL CORPORATION (US) 2010-05-14 WO disclosed
US-20100119741-A1 Waterborne Adhesive HENKEL CORPORATION 2010-05-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11685702-B2 Method for producing arene compounds and arene compounds produced by the same PFAS, FRK, AGPAT2 CYP2C19 384/4885HIF1A 2300/4885MAPK1 1365/4885
US-12554198-B2 Functional hydrogen silsesquioxane resins and the use thereof MACF1, RTF1, ERCC4 CYP2C19 2368/4885HIF1A 214/4885MAPK1 2966/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.