SCHEMBL6323804

SCHEMBL6323804

CCOC(=O)c1cccc(NC(=O)NS(=O)(=O)c2cccc(C)c2)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.57
CA1 P00915 1/20 0.57
CA2 P00918 1/20 0.57
CA9 Q16790 1/20 0.57
SMN1; SMN2 Q16637 3/20 0.57
RAB9A P51151 3/20 0.57
KMT2A Q03164 2/20 0.57
MAPT P10636 2/20 0.57
NPC1 O15118 2/20 0.57
MEN1 O00255 1/20 0.57
NPSR1 Q6W5P4 1/20 0.56
LMNA P02545 1/20 0.55
TP53 P04637 1/20 0.54
ALDH1A1 P00352 1/20 0.54
TSHR P16473 1/20 0.54
FBP1 P09467 9/20 0.53
NAMPT P43490 1/20 0.53
CYP1A2 P05177 1/20 0.52
CYP2C9 P11712 1/20 0.52
HPGD P15428 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1929592 0.93 FBP1 (0.53) CA12CA1CA2CA9KMT2A
SCHEMBL6324631 0.92 ALDH1A1 (0.56) CA12CA1CA2CA9SMN1; SMN2
SCHEMBL1931132 0.91 FBP1 (0.54) SMN1; SMN2RAB9AKMT2ANPC1MEN1
SCHEMBL1929181 0.91 FBP1 (0.54) SMN1; SMN2RAB9AKMT2ANPC1FBP1
SCHEMBL6324678 0.91 SMN1; SMN2 (0.60) CA12CA1CA2CA9SMN1; SMN2
SCHEMBL6325357 0.91 SMN1; SMN2 (0.58) CA12CA1CA2CA9SMN1; SMN2
SCHEMBL1930806 0.90 FBP1 (0.55) SMN1; SMN2RAB9AKMT2ANPC1MEN1
SCHEMBL1928907 0.90 FBP1 (0.55) SMN1; SMN2RAB9AKMT2ANPC1MEN1
SCHEMBL1929818 0.90 FBP1 (0.55) SMN1; SMN2RAB9AKMT2ANPC1MEN1
SCHEMBL1930100 0.90 FBP1 (0.55) SMN1; SMN2RAB9AKMT2ANPC1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6858565-B2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2005-02-22 US disclosed
US-20030040434-A1 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2003-02-27 US disclosed
EP-1264707-A2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2002-12-11 EP disclosed