SCHEMBL1929592

SCHEMBL1929592

Cc1cccc(S(=O)(=O)NC(=O)Nc2cccc(C(=O)OCOC(=O)c3cccc(NC(=O)NS(=O)(=O)c4cccc(C)c4)c3)c2)c1

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 15/20 0.53
NLRP3 Q96P20 1/20 0.52
KCNA1 Q09470 1/20 0.51
KCNAB1 Q14722 1/20 0.51
GPR17 Q13304 1/20 0.50
CA12 O43570 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CA9 Q16790 1/20 0.49
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6323804 0.93 CA12 (0.57) FBP1NLRP3CA12CA1CA2
SCHEMBL1931132 0.91 FBP1 (0.54) FBP1NLRP3KCNA1KCNAB1MEN1
SCHEMBL1929181 0.91 FBP1 (0.54) FBP1NLRP3KCNA1KCNAB1KMT2A
SCHEMBL1930100 0.90 FBP1 (0.55) FBP1NLRP3KCNA1KCNAB1MEN1
SCHEMBL1930806 0.90 FBP1 (0.55) FBP1NLRP3KCNA1KCNAB1MEN1
SCHEMBL6324631 0.90 ALDH1A1 (0.56) FBP1NLRP3KCNA1KCNAB1CA12
SCHEMBL1928907 0.90 FBP1 (0.55) FBP1NLRP3KCNA1KCNAB1MEN1
SCHEMBL1928977 0.90 FBP1 (0.55) FBP1NLRP3KCNA1KCNAB1MEN1
SCHEMBL1929818 0.90 FBP1 (0.55) FBP1NLRP3KCNA1KCNAB1MEN1
SCHEMBL1928909 0.90 LMNA (0.61) NLRP3KCNA1KCNAB1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7956007-B2 support and a heat-sensitive recording layer, the heat-sensitive recording layer comprising a colorless or pale-colored basic dye and a developer, the developer being 4-allyloxy-4'-hydroxydiphenylsulfone and the heat-sensitive recording layer further comprising a compound represented by formula (I): OJI PAPER CO., LTD. (JP) 2011-06-07 US disclosed
EP-1842688-B1 HEAT-SENSITIVE RECORDING MATERIAL OJI PAPER CO (JP) 2009-10-07 EP disclosed
US-20080167184-A1 Heat-Sensitive Recording Material OJI PAPER CO., LTD. (JP) 2008-07-10 US disclosed
US-7312177-B2 Thermosensitive recording materials OJI PAPER CO., LTD. (JP) 2007-12-25 US disclosed
EP-1512545-B1 Thermosensitive recording materials OJI PAPER CO (JP) 2007-11-07 EP disclosed
EP-1842688-A1 HEAT-SENSITIVE RECORDING MATERIAL Oji Paper Co., Ltd. (JP) 2007-10-10 EP disclosed
US-20050054528-A1 Thermosensitive recording materials OJI PAPER CO., LTD. (JP) 2005-03-10 US disclosed
EP-1512545-A1 Thermosensitive recording materials Oji Paper Co., Ltd. (JP) 2005-03-09 EP disclosed