Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6324295 | 0.86 | PIN1 (1.00) | PIN1 | |
| SCHEMBL6325242 | 0.83 | PIN1 (0.76) | PIN1 | |
| SCHEMBL6326102 | 0.80 | PIN1 (0.57) | PIN1 | |
| SCHEMBL6272051 | 0.79 | PIN1 (0.82) | PIN1 | |
| SCHEMBL6329757 | 0.76 | PIN1 (1.00) | PIN1 | |
| SCHEMBL16550466 | 0.76 | PIN1 (1.00) | PIN1 | |
| SCHEMBL16550468 | 0.76 | PIN1 (1.00) | PIN1 | |
| SCHEMBL6324740 | 0.76 | KMT2A (0.47) | PIN1 | |
| SCHEMBL6329760 | 0.75 | PIN1 (1.00) | PIN1 | |
| SCHEMBL6326344 | 0.75 | PIN1 (1.00) | PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050250742-A1 | Phosphate/sulfate ester compounds and pharmaceutical composition for inhibiting protein interacting NIMA (PIN1) | PFIZER INC. | 2005-11-10 | — | — | US | disclosed |
| US-6894050-B2 | 5-HT receptor ligands and uses thereof | PFIZER INC. (US) | 2005-05-17 | — | — | US | disclosed |
| US-20050090503-A1 | 5-HT receptor ligands and uses thereof | PFIZER INC | 2005-04-28 | — | — | US | disclosed |
| US-20030125334-A1 | 5-HT receptor ligands and uses thereof | CHIANG PHOEBE (US) | 2003-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250742-A1 | Phosphate/sulfate ester compounds and pharmaceutical composition for inhibiting protein interacting NIMA (PIN1) | PIN1, PSTPIP2, NIM1K | PIN1 1/4885GLA 3781/4885 |
| US-20050090503-A1 | 5-HT receptor ligands and uses thereof | HTR2A, HTR1A, HTR5A | PIN1 4035/4885GLA 2454/4885 |
| US-20030125334-A1 | 5-HT receptor ligands and uses thereof | HTR1A, HTR2A, HTR5A | PIN1 4143/4885GLA 2535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.