Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1555139 | 0.98 | CYP1A2 (0.38) | CYP1A2POLBL3MBTL1HTTGLA | |
| SCHEMBL14156244 | 0.78 | POLB (0.33) | POLBL3MBTL1NOTUM | |
| SCHEMBL20107644 | 0.75 | CDK8 (0.32) | — | |
| SCHEMBL30366081 | 0.73 | CYP1A2 (0.33) | CYP1A2POLBL3MBTL1 | |
| SCHEMBL6643747 | 0.72 | LMNA (0.40) | POLB | |
| SCHEMBL6496071 | 0.72 | ALDH1A1 (0.32) | CYP1A2POLBL3MBTL1 | |
| SCHEMBL8529960 | 0.72 | KDM4E (0.37) | CYP1A2POLBL3MBTL1 | |
| SCHEMBL9139040 | 0.72 | CYP1A2 (0.36) | CYP1A2POLBL3MBTL1 | |
| SCHEMBL28726409 | 0.70 | L3MBTL1 (0.52) | CYP1A2POLBL3MBTL1HTT | |
| SCHEMBL7841671 | 0.69 | CYP1A2 (0.31) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050256003-A1 | Novel herbicides | SYNGENTA CROP PROTECTION, INC. | 2005-11-17 | — | — | US | disclosed |
| EP-1513829-A2 | NICOTINOYL DERIVATIVES AS HERBICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003106448-A2 | NOVEL HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2003-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256003-A1 | Novel herbicides | DDT, CYP4F11, CYP1B1 | CYP1A2 43/4885POLB 4285/4885L3MBTL1 2140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.