SCHEMBL6324128

SCHEMBL6324128

Cc1ccc(S(=O)(=O)NC(=O)Nc2cccc(C(=O)Oc3ccc(Cl)cc3)c2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.55
KMT2A Q03164 4/20 0.53
MEN1 O00255 2/20 0.53
TCF4 P15884 1/20 0.53
CTNNB1 P35222 1/20 0.53
MAPT P10636 5/20 0.52
NPC1 O15118 2/20 0.52
RAB9A P51151 2/20 0.52
ALDH1A1 P00352 3/20 0.51
GAA P10253 3/20 0.51
CYP2C9 P11712 2/20 0.51
CYP2C19 P33261 2/20 0.51
IDH1 O75874 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
RECQL P46063 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2D6 P10635 1/20 0.48
HSD17B10 Q99714 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7602126 0.95 LMNA (0.61) LMNAKMT2AMEN1TCF4CTNNB1
SCHEMBL7595935 0.90 LMNA (0.65) LMNAKMT2AMEN1TCF4CTNNB1
SCHEMBL6324125 0.84 LMNA (0.57) LMNAKMT2AMEN1TCF4CTNNB1
SCHEMBL6321981 0.84 TCF4 (0.73) LMNAKMT2AMEN1TCF4CTNNB1
SCHEMBL31261058 0.84 LMNA (0.61) LMNAKMT2AMEN1TCF4CTNNB1
SCHEMBL5187572 0.82 LMNA (0.70) LMNAKMT2AMEN1MAPTRAB9A
SCHEMBL7602130 0.82 LMNA (0.59) LMNAKMT2AMEN1TCF4CTNNB1
SCHEMBL6330701 0.81 TP53 (0.64) LMNAKMT2AMEN1TCF4CTNNB1
SCHEMBL1928909 0.81 LMNA (0.61) LMNAKMT2AMEN1TCF4CTNNB1
SCHEMBL6331726 0.81 MAPT (0.55) LMNAKMT2AMEN1MAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6858565-B2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2005-02-22 US disclosed
US-20030040434-A1 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2003-02-27 US disclosed
EP-1264707-A2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2002-12-11 EP disclosed