SCHEMBL6324299

SCHEMBL6324299

CCOS(=O)(=O)c1ccccc1NC(=O)NS(=O)(=O)C1CCCCC1

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.42
MRGPRX1 Q96LB2 9/20 0.40
MEN1 O00255 3/20 0.39
HTT P42858 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
KDM4E B2RXH2 2/20 0.38
TSHR P16473 1/20 0.37
TSPO P30536 1/20 0.36
ALDH1A1 P00352 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6326717 0.91 MRGPRX1 (0.42) KMT2AMRGPRX1MEN1HTTSMN1; SMN2
SCHEMBL6329861 0.89 KMT2A (0.39) KMT2AMRGPRX1MEN1HTTSMN1; SMN2
SCHEMBL6321845 0.87 KDM4E (0.43) KMT2AMRGPRX1MEN1HTTSMN1; SMN2
SCHEMBL6323995 0.84 TAS1R3 (0.42) KMT2AMRGPRX1MEN1HTTSMN1; SMN2
SCHEMBL6329992 0.81 SMN1; SMN2 (0.40) KMT2AMRGPRX1MEN1HTTSMN1; SMN2
SCHEMBL6325457 0.78 MRGPRX1 (0.41) KMT2AMRGPRX1MEN1HTTSMN1; SMN2
SCHEMBL6324376 0.74 MRGPRX1 (0.43) KMT2AMRGPRX1MEN1HTTSMN1; SMN2
SCHEMBL7599829 0.74 KDM4E (0.41) KMT2AMRGPRX1MEN1HTTSMN1; SMN2
SCHEMBL7598898 0.73 KMT2A (0.42) KMT2AMRGPRX1MEN1HTTSMN1; SMN2
SCHEMBL6323916 0.72 MRGPRX1 (0.40) KMT2AMRGPRX1MEN1HTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6858565-B2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2005-02-22 US disclosed
US-20030040434-A1 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2003-02-27 US disclosed