Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX1 | Q96LB2 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.35 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.34 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6329861 | 0.94 | KMT2A (0.39) | MRGPRX1KMT2ASMN1; SMN2MEN1HTT | |
| SCHEMBL6324299 | 0.91 | KMT2A (0.42) | MRGPRX1KMT2ASMN1; SMN2MEN1HTT | |
| SCHEMBL6321845 | 0.85 | KDM4E (0.43) | MRGPRX1KMT2ASMN1; SMN2MEN1HTT | |
| SCHEMBL6323995 | 0.82 | TAS1R3 (0.42) | MRGPRX1KMT2ASMN1; SMN2MEN1HTT | |
| SCHEMBL6329992 | 0.80 | SMN1; SMN2 (0.40) | MRGPRX1KMT2ASMN1; SMN2MEN1HTT | |
| SCHEMBL6324376 | 0.79 | MRGPRX1 (0.43) | MRGPRX1KMT2ASMN1; SMN2MEN1HTT | |
| SCHEMBL6323916 | 0.75 | MRGPRX1 (0.40) | MRGPRX1KMT2ASMN1; SMN2MEN1HTT | |
| SCHEMBL6325457 | 0.74 | MRGPRX1 (0.41) | MRGPRX1KMT2ASMN1; SMN2MEN1HTT | |
| SCHEMBL7599829 | 0.72 | KDM4E (0.41) | MRGPRX1KMT2ASMN1; SMN2MEN1HTT | |
| SCHEMBL7598898 | 0.71 | KMT2A (0.42) | MRGPRX1KMT2ASMN1; SMN2MEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024150250-A1 | A PROCESS FOR THE PREPARATION OF ATOGEPANT AND ITS INTERMEDIATES | MSN LABORATORIES PRIVATE LIMITED, R&D CENTER (IN) | 2024-07-18 | — | — | WO | disclosed |
| US-20140322646-A1 | ABLATION IMAGEABLE LITHOGRAPHIC PRINTING PLATE | NPEC INC. | 2014-10-30 | — | — | US | disclosed |
| US-20140065407-A1 | MANUFACTURE OF LITHOGRAPHIC PRINTING PLATE PRECURSORS FOR ABLATION IMAGING | KODAK REALTY INC. | 2014-03-06 | — | — | US | disclosed |
| WO-2012106169-A1 | METHOD FOR PREPARING LITHOGRAPHIC PRINTING PLATES | EASTMAN KODAK COMPANY (US) | 2012-08-09 | — | — | WO | disclosed |
| US-20120192741-A1 | METHOD FOR PREPARING LITHOGRAPHIC PRINTING PLATES | NPEC INC. | 2012-08-02 | — | — | US | disclosed |
| WO-2012099833-A1 | PREPARING LITHOGRAPHIC PRINTING PLATES BY ABLATION IMAGING | EASTMAN KODAK COMPANY (US) | 2012-07-26 | — | — | WO | disclosed |
| US-20120189770-A1 | PREPARING LITHOGRAPHIC PRINTING PLATES BY ABLATION IMAGING | KODAK REALTY INC. | 2012-07-26 | — | — | US | disclosed |
| US-20050239107-A1 | Trapped photochromes and thermochromes and uses for chromogenic detection, including detection of airborne contaminants | MERIS INVESTMENT INC. | 2005-10-27 | — | — | US | disclosed |
| US-6858565-B2 | Thermosensitive recording material and novel color developer compounds | OJI PAPER CO., LTD. (JP) | 2005-02-22 | — | — | US | disclosed |
| US-20030040434-A1 | Thermosensitive recording material and novel color developer compounds | OJI PAPER CO., LTD. (JP) | 2003-02-27 | — | — | US | disclosed |
| EP-1264707-A2 | Thermosensitive recording material and novel color developer compounds | OJI PAPER CO., LTD. (JP) | 2002-12-11 | — | — | EP | disclosed |
| EP-0912567-B1 | CARBOLINE DERIVATIVES | ICOS CORP (US) | 2002-04-10 | — | — | EP | disclosed |
| US-6306870-B1 | PHOSPHODIESTERASE ENZYME INHIBITORS, CARDIOVASCULAR DISORDERS AND SEXUAL DISORDERS | ICOS CORPORATION | 2001-10-23 | — | — | US | disclosed |
| US-6117881-A | POTENT AND SELECTIVE INHIBITORS OF CYCLIC GUANOSINE 3',5'-MONOPHOSPHATE SPECIFIC PHOSPHODIESTERASE | ICOS CORPORATION (US) | 2000-09-12 | — | — | US | disclosed |
| US-6043252-A | A POTENT AND SELECTIVE INHIBITORS OF CYCLIC GUANOSINE 3',5'-MONOPHOSPHATE SPECIFIC PHOSPHODIESTERASE (CGMP-SPECIFIC PDE); TREATING CARDIOVASCULAR DISORDERS AND ERECTILE DYSFUNCTION | ICOS CORPORATION (US) | 2000-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239107-A1 | Trapped photochromes and thermochromes and uses for chromogenic detection, including detection of airborne contaminants | CBX3, CBX6, CBX2 | MRGPRX1 2597/4885KMT2A 734/4885SMN1; SMN2 4522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.