SCHEMBL7597834

SCHEMBL7597834

CCCOC(=O)c1cccc(N(C(N)=O)S(=O)(=O)c2ccccc2)c1

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.51
TDP1 Q9NUW8 1/20 0.43
ALDH1A1 P00352 4/20 0.42
MAPT P10636 2/20 0.41
KDM4E B2RXH2 1/20 0.41
STS P08842 1/20 0.41
KMT2A Q03164 3/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
MEN1 O00255 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7649036 0.87 LMNA (0.55) LMNATDP1ALDH1A1MAPTSTS
SCHEMBL7596654 0.82 CNR2 (0.43) LMNAALDH1A1MAPTSTS
SCHEMBL7601325 0.81 MAPT (0.53) LMNATDP1ALDH1A1MAPTKMT2A
SCHEMBL6324423 0.80 KMT2A (0.46) LMNATDP1ALDH1A1MAPTKMT2A
SCHEMBL7599783 0.78 ESR1 (0.44) LMNAALDH1A1MAPTKDM4ESTS
SCHEMBL7601389 0.77 LMNA (0.44) LMNATDP1ALDH1A1MAPTL3MBTL1
SCHEMBL20267173 0.76 LMNA (0.58) LMNATDP1ALDH1A1KDM4ESTS
SCHEMBL11793288 0.75 LMNA (0.60) LMNATDP1ALDH1A1MAPTKDM4E
SCHEMBL7602168 0.74 CA12 (0.46) LMNAALDH1A1KDM4E
SCHEMBL174224 0.74 KMT2A (0.62) ALDH1A1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1264707-A2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2002-12-11 EP disclosed