Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 9/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8312721 | 0.91 | PLA2G7 (0.39) | HPGDCAPN1ALDH1A1PKMSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6325008 | 0.89 | F10 (0.40) | HPGDCAPN1ALDH1A1NPC1RAB9A | |
| SCHEMBL6331770 | 0.79 | F10 (0.47) | HPGDCAPN1PKMSMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL6329967 | 0.79 | HPGD (0.41) | HPGDCAPN1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL6324477 | 0.77 | HAT1 (0.42) | HPGDALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8312535 | 0.77 | CAPN1 (0.38) | HPGDCAPN1PKMSMN1; SMN2NPC1 | |
| SCHEMBL6324855 | 0.77 | CDK8 (0.41) | HPGDALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL3003536 | 0.77 | F10 (0.41) | HPGDCAPN1ALDH1A1SMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL6331804 | 0.76 | F10 (0.40) | HPGDCAPN1ALDH1A1SMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL6323304 | 0.70 | F10 (0.46) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050107409-A1 | Aromatic bicyclic compounds, preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107409-A1 | Aromatic bicyclic compounds, preparation thereof and their use as pharmaceutical compositions | F12, F2, F11 | HPGD 1428/4885CAPN1 2654/4885ALDH1A1 1078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.