Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK8 | P49336 | 10/20 | 0.41 |
| ▸ | CCNC | P24863 | 9/20 | 0.41 |
| ▸ | CDK19 | Q9BWU1 | 3/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.40 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6331290 | 0.89 | CDK1 (0.48) | CDK8CCNCCDK19KDM1ACDK1 | |
| Hydrochloric Acid SCHEMBL6329967 | 0.87 | HPGD (0.41) | ALDH1A1HSD17B10HPGDMAPTNPC1 | |
| SCHEMBL6324477 | 0.85 | HAT1 (0.42) | CDK8CCNCCDK19CDK1MAP4K2 | |
| SCHEMBL6326964 | 0.84 | KDM1A (0.46) | CDK8CCNCCDK19KDM1ACDK1 | |
| SCHEMBL6326969 | 0.83 | CDK8 (0.46) | CDK8CCNCCDK19KDM1ACDK1 | |
| SCHEMBL6331440 | 0.77 | CDK1 (0.46) | CDK8CCNCCDK19KDM1ACDK1 | |
| SCHEMBL6324439 | 0.77 | HPGD (0.39) | ALDH1A1CYP1A2CYP3A4CYP2C9MAPK1 | |
| SCHEMBL8312721 | 0.76 | PLA2G7 (0.39) | ALDH1A1CYP1A2CYP3A4CYP2C9MAPK1 | |
| SCHEMBL6340535 | 0.76 | SLC6A9 (0.44) | ALDH1A1HSD17B10HPGDMAPTNPC1 | |
| Hydrochloric Acid SCHEMBL6325008 | 0.76 | F10 (0.40) | ALDH1A1CYP1A2CYP3A4CYP2C9MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050107409-A1 | Aromatic bicyclic compounds, preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-05-19 | — | — | US | disclosed |
| WO-2004080970-A1 | NOVEL BICYCLIC AROMATIC COMPOUNDS, THE PRODUCTION AND USE THEREOF IN THE FORM OF DRUGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107409-A1 | Aromatic bicyclic compounds, preparation thereof and their use as pharmaceutical compositions | F12, F2, F11 | CDK8 765/4885CCNC 1916/4885CDK19 502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.