Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 2/20 | 0.49 |
| ▸ | HTR6 | P50406 | 6/20 | 0.46 |
| ▸ | IDE | P14735 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20919965 | 0.89 | HTR6 (0.52) | HTR6METACHEPIK3CA | |
| SCHEMBL5704817 | 0.85 | HTR6 (0.64) | STSHTR6 | |
| SCHEMBL5704869 | 0.84 | HTR6 (0.66) | STSHTR6METSMN1; SMN2MAPT | |
| SCHEMBL5705003 | 0.83 | HTR6 (0.53) | STSHTR6MET | |
| SCHEMBL5704838 | 0.82 | HTR6 (0.54) | STSHTR6METMAPT | |
| SCHEMBL5704927 | 0.82 | HTR6 (0.60) | STSHTR6 | |
| SCHEMBL5705141 | 0.82 | HTR6 (0.53) | STSHTR6MAPK1GAAMAPT | |
| SCHEMBL5705076 | 0.81 | HTR6 (0.61) | STSHTR6MEN1KMT2AALDH1A1 | |
| SCHEMBL5704768 | 0.81 | HTR6 (0.52) | STSHTR6MAPT | |
| SCHEMBL5704770 | 0.80 | HTR6 (0.65) | STSHTR6MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050090496-A1 | Sulphonyl compounds with 5-ht6 receptor affinity | GLAXO GROUP LIMITED (GB) | 2005-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090496-A1 | Sulphonyl compounds with 5-ht6 receptor affinity | HTR6, HTR4, HTR5A | STS 113/4885HTR6 1/4885IDE 4479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.