Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.52 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | VNN1 | O95497 | 3/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | ASPH | Q12797 | 1/20 | 0.43 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.43 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6318631 | 0.83 | MAP2K1 (0.56) | MAP2K1MAP2K2KDM4EALDH1A1HPGD | |
| SCHEMBL15059077 | 0.79 | RAB9A (0.51) | GAAMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL6317553 | 0.78 | MAP2K1 (0.61) | MAP2K1MAP2K2 | |
| SCHEMBL5622895 | 0.78 | MAP2K1 (0.61) | MAP2K1MAP2K2 | |
| SCHEMBL2294877 | 0.75 | PDE4B (0.60) | MAP2K1MAP2K2GAAMAPTSMN1; SMN2 | |
| SCHEMBL6505710 | 0.75 | MAP2K1 (0.57) | MAP2K1MAP2K2TP53 | |
| SCHEMBL15270392 | 0.73 | GAA (0.56) | GAAMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL31252847 | 0.73 | GAA (0.56) | GAAMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL3883164 | 0.72 | IDO1 (0.47) | MAP2K1MAP2K2GAAMAPTALDH1A1 | |
| SCHEMBL4847270 | 0.71 | GAA (0.53) | GAAMAPTKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050049276-A1 | Imidazopyridines and triazolopyridines | WARNER-LAMBERT COMPANY, LLC | 2005-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050049276-A1 | Imidazopyridines and triazolopyridines | QDPR, DPYD, CYP3A5 | MAP2K1 2549/4885MAP2K2 2473/4885GAA 871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.